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Do any non-drug treatments help back pain? Here’s what the evidence says

<div class="theconversation-article-body"> Jason, a 42-year-old father of two, has been battling back pain for weeks. Scrolling through his phone, he sees ad after ad promising relief: chiropractic alignments, acupuncture, back braces, vibrating massage guns and herbal patches. His GP told him to “stay active”, but what does that even mean when every movement hurts? Jason wants to avoid strong painkillers and surgery, but with so many options (and opinions), it’s hard to know what works and what’s just marketing hype. If Jason’s experience sounds familiar, you’re not alone. Back pain is one of the most common reasons people visit a doctor. It can be challenging to manage, mainly due to widespread <a href="https://theconversation.com/having-good-posture-doesnt-prevent-back-pain-and-bad-posture-doesnt-cause-it-183732">misunderstandings</a> and the <a href="https://ebm.bmj.com/content/early/2025/03/02/bmjebm-2024-112974">overwhelming number</a> of ineffective and uncertain treatments promoted. We assessed the best available evidence of non-drug and non-surgical treatments to alleviate low back pain. <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014691.pub2/full">Our review</a> – published today by the independent, international group the Cochrane Collaboration – includes 31 Cochrane systematic reviews, covering 97,000 people with back pain. It <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014691.pub2/full">shows</a> bed rest doesn’t work for back pain. Some of the treatments that do work can depend on how long you’ve been in pain. <h2>Is back pain likely to be serious?</h2> There are different types of low back pain. It can: <ul> <li>be short-lived, lasting less than six weeks (acute back pain)</li> <li>linger for a bit longer, for six to twelve weeks (sub-acute)</li> <li>stick around for months and even years (chronic, defined as more than 12 weeks).</li> </ul> In <a href="https://www.thelancet.com/article/S0140-6736(16)30970-9/abstract">most cases</a> (90-95%), back pain is non-specific and cannot be reliably linked to a specific cause or underlying disease. This includes common structural changes seen in x-rays and MRIs of the spine. For this reason, imaging of the back is <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60172-0/abstract">only</a> recommended in rare situations – typically when there’s a clear suspicion of serious back issues, such as after physical trauma or when there is numbness or loss of sensation in the groin or legs. Many people expect to receive <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013815.pub2/full">painkillers</a> for their back pain or even surgery, but these are no longer the front-line treatment options due to limited benefits and the high risk of harm. International <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30489-6/fulltext">clinical guidelines</a> recommend people choose non-drug and non-surgical treatments to relieve their pain, improve function and reduce the distress commonly associated with back pain. So what works for different types of pain? Here’s what <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014691.pub2/full">our review found</a> when researchers compared these treatments with standard care (the typical treatment patients usually receive) or no treatment. <h2>What helps for short-term back pain</h2> 1. Stay active – don’t rest in bed If your back pain is new, the best advice is also one of the simplest: keep moving despite the pain. Changing the way you move and use your body to protect it, or resting in bed, can seem like to right way to respond to pain – and may have even been recommended in the past. But we know know this excessive protective behaviour can make it harder to return to meaningful activities. This doesn’t mean pushing through pain or hitting the gym, but instead, trying to maintain your usual routines as much as possible. Evidence suggests that doing so won’t make your pain worse, and may improve it. 2. Multidisciplinary care, if pain lingers For pain lasting six to 12 weeks, multidisciplinary treatment is likely to reduce pain compared to standard care. This involves a coordinated team of doctors, physiotherapists and psychologists working together to address the many factors contributing to your back pain persisting: <ul> <li> neurophysiological influences refer to how your nervous system is currently processing pain. It can make you more sensitive to signals from movements, thoughts, feelings and environment </li> <li> psychological factors include how your thoughts, feelings and behaviours affect your pain system and, ultimately, the experience of pain you have </li> <li> occupational factors include the physical demands of your job and how well you can manage them, as well as aspects like low job satisfaction, all of which can contribute to ongoing pain. </li> </ul> <h2>What works for chronic back pain</h2> Once pain has been around for more than 12 weeks, it can become more difficult to treat. But relief is still possible. Exercise therapy Exercise – especially programs tailored to your needs and preferences – is likely to reduce pain and help you move better. This could include aerobic activity, strength training or Pilates-based movements. It doesn’t seem to matter what type of exercise you do – it matters more that you are consistent and have the right level of supervision, especially early on. Multidisciplinary treatment As with short-term pain, coordinated care involving a mix of physical, occupational and psychological approaches likely works better than usual care alone. Psychological therapies Psychological therapies for chronic pain include approaches to help people change thinking, feelings, behaviours and reactions that might sustain persistent pain. These approaches are likely to reduce pain, though they may not be as effective in improving physical function. Acupuncture Acupuncture probably reduces pain and improves how well you can function compared to placebo or no treatment. While some debate remains about how it works, the evidence suggests potential benefits for some people with chronic back pain. <h2>What doesn’t work or still raises uncertainty?</h2> The review found that many commonly advertised treatments still have uncertain benefits or probably do not benefit people with back pain. Spinal manipulation, for example, has uncertain benefits in acute and chronic back pain, and it likely does not improve how well you function if you have acute back pain. Traction, which involves stretching the spine using weights or pulleys, probably doesn’t help with chronic back pain. Despite its popularity in some circles, there’s little evidence that it works. There isn’t enough reliable data to determine whether advertised treatments – such back braces, vibrating massage guns and herbal patches – are effective. <h2>How can you use the findings?</h2> If you have back pain, start by considering how long you’ve had it. Then explore treatment options that research supports and discuss them with your GP, psychologist or physiotherapist. Your health provider should reassure you about the importance of gradually increasing your activity to resume meaningful work, social and life activities. They should also support you in making informed decisions about which treatments are most appropriate for you at this stage. <img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/253122/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" />By <a href="https://theconversation.com/profiles/rodrigo-rossi-nogueira-rizzo-1544189">Rodrigo Rossi Nogueira Rizzo</a>, Postdoctoral Research Fellow, <a href="https://theconversation.com/institutions/neuroscience-research-australia-976">Neuroscience Research Australia</a> and <a href="https://theconversation.com/profiles/aidan-cashin-2355450">Aidan Cashin</a>, NHMRC Emerging Leadership Fellow, <a href="https://theconversation.com/institutions/neuroscience-research-australia-976">Neuroscience Research Australia</a> This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/do-any-non-drug-treatments-help-back-pain-heres-what-the-evidence-says-253122">original article</a>. Image: Shutterstock </div>

Body

"A miracle": Man walks away from horror crash

A man has walked away with only minor injuries after surviving a horrific crash in Sydney's north. The horrific scene unfolded when the man's car was crushed after he collided with a truck on the Spit Bridge in Manly on Monday morning. The man in his 40s was cut out of the wreckage by firefighters, with NSW Ambulance confirming that he was taken to Royal North Shore Hospital after sustaining minor injuries to his back and neck. Many people were stunned after seeing images of the mangled vehicle, wondering how the driver managed to walk away relatively unscathed. “How good are those first responders to get him out alive. Bloody heroes every single one of them,” one person said, while another added, “That is a miracle.” “So glad he is OK! He should buy a lotto ticket, thank you to the amazing first responses you do an amazing job,” another said. Fire and Rescue NSW Superintendent Andrew Dewberry told <a href="https://manlyobserver.com.au/spit-bridge-closed-after-car-crushed/" target="_blank" rel="noopener">The Manly Observer</a> that the car was "completely crushed and mangled" and it was a "miracle" he survived. Two of three outbound lanes were closed on the bridge for about an hour as emergency crews worked to free the person from the vehicle and clear the scene. Many commuters were stuck in the heavy traffic delays, with dozens of people fleeing standstill buses and trekking along the highway to escape the chaos. Image credits: The Manly Observer

Caring

How we diagnose and define obesity is set to change – here’s why, and what it means for treatment

<div class="theconversation-article-body"> <a href="https://theconversation.com/profiles/louise-baur-5284">Louise Baur</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>; <a href="https://theconversation.com/profiles/john-b-dixon-11630">John B. Dixon</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/priya-sumithran-1529047">Priya Sumithran</a>, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a>, and <a href="https://theconversation.com/profiles/wendy-a-brown-1665">Wendy A. Brown</a>, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a> Obesity is <a href="https://www.niddk.nih.gov/health-information/weight-management/adult-overweight-obesity/health-risks#:%7E:text=Having%20overweight%20or%20obesity%20increases,the%20cells%20in%20your%20body">linked to</a> many common diseases, such as type 2 diabetes, heart disease, fatty liver disease and knee osteoarthritis. Obesity is currently defined using a person’s body mass index, or BMI. This is <a href="https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight">calculated</a> as weight (in kilograms) divided by the square of height (in metres). In people of European descent, the BMI for obesity is 30 kg/m² and over. But the risk to health and wellbeing is not determined by weight – and therefore BMI – alone. We’ve been part of a global collaboration that has spent the past two years discussing how this should change. Today we publish how we think obesity should be defined and why. As we outline in <a href="https://www.thelancet.com/commissions/clinical-obesity">The Lancet</a>, having a larger body shouldn’t mean you’re diagnosed with “clinical obesity”. Such a diagnosis should depend on the level and location of body fat – and whether there are associated health problems. <h2>What’s wrong with BMI?</h2> The risk of ill health depends on the relative percentage of fat, bone and muscle making up a person’s body weight, as well as where the fat is distributed. Athletes with a relatively high muscle mass, for example, may have a higher BMI. Even when that athlete has a BMI over 30 kg/m², their higher weight is due to excess muscle rather than excess fatty tissue. People who carry their excess fatty tissue <a href="https://www.abc.net.au/news/health/2017-09-06/waist-size-why-it-matters-and-when-its-a-risk/8839708">around their waist</a> are at greatest risk of the health problems associated with obesity. Fat stored deep in the abdomen and around the internal organs can release damaging molecules into the blood. These can then <a href="https://theconversation.com/body-fat-deep-below-the-surface-is-a-toxic-risk-especially-for-your-heart-146307">cause problems</a> in other parts of the body. But BMI alone does not tell us whether a person has health problems related to excess body fat. People with excess body fat don’t always have a BMI over 30, meaning they are not investigated for health problems associated with excess body fat. This might occur in a very tall person or in someone who tends to store body fat in the abdomen but who is of a “healthy” weight. On the other hand, others who aren’t athletes but have excess fat may have a high BMI but no associated health problems. BMI is therefore an imperfect tool to help us diagnose obesity. <h2>What is the new definition?</h2> The goal of the <a href="https://pubmed.ncbi.nlm.nih.gov/36878238">Lancet Diabetes & Endocrinology Commission on the Definition and Diagnosis of Clinical Obesity </a> was to develop an approach to this definition and diagnosis. The commission, established in 2022 and led from King’s College London, has brought together 56 experts on aspects of obesity, including people with lived experience. The commission’s <a href="https://www.thelancet.com/commissions/clinical-obesity">definition and new diagnostic criteria</a> shifts the focus from BMI alone. It incorporates other measurements, such as waist circumference, to confirm an excess or unhealthy distribution of body fat. We define two categories of obesity based on objective signs and symptoms of poor health due to excess body fat. 1. Clinical obesity A person with clinical obesity has signs and symptoms of ongoing organ dysfunction and/or difficulty with day-to-day activities of daily living (such as bathing, going to the toilet or dressing). There are 18 diagnostic criteria for clinical obesity in adults and 13 in children and adolescents. These include: <ul> <li> breathlessness caused by the effect of obesity on the lungs </li> <li> obesity-induced heart failure </li> <li> raised blood pressure </li> <li> fatty liver disease </li> <li> abnormalities in bones and joints that limit movement in children. </li> </ul> 2. Pre-clinical obesity A person with pre-clinical obesity has high levels of body fat that are not causing any illness. People with pre-clinical obesity do not have any evidence of reduced tissue or organ function due to obesity and can complete day-to-day activities unhindered. However, people with pre-clinical obesity are generally at higher risk of developing diseases such as heart disease, some cancers and type 2 diabetes. <h2>What does this mean for obesity treatment?</h2> Clinical obesity is a disease requiring access to effective health care. For those with clinical obesity, the focus of health care should be on improving the health problems caused by obesity. People should be offered evidence-based treatment options after discussion with their health-care practitioner. <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01210-8/abstract">Treatment</a> will <a href="https://www.thelancet.com/journals/landia/article/PIIS2213-8587(22)00047-X/fulltext">include</a> management of obesity-associated complications and may include specific obesity treatment aiming at decreasing fat mass, such as: <ul> <li> support for <a href="https://www.obesityevidencehub.org.au/collections/treatment/behavioural-interventions-for-the-management-of-overweight-and-obesity-in-adults">behaviour change</a> <a href="https://www.obesityevidencehub.org.au/collections/treatment/managing-overweight-and-obesity-in-children-and-adolescents">around</a> diet, physical activity, sleep and screen use </li> <li> obesity-management medications to reduce appetite, lower weight and <a href="https://www.obesityevidencehub.org.au/collections/treatment/medication-and-surgery-for-the-treatment-of-overweight-and-obesity-in-adults">improve health</a> outcomes such as blood glucose (sugar) and blood pressure </li> <li> metabolic <a href="https://theconversation.com/thinking-about-bariatric-surgery-for-weight-loss-heres-what-to-consider-184153">bariatric surgery</a> to treat obesity or reduce weight-related health complications. </li> </ul> <h2>Should pre-clinical obesity be treated?</h2> For those with pre-clinical obesity, health care should be about risk-reduction and prevention of health problems related to obesity. This may require health counselling, including support for health behaviour change, and monitoring over time. Depending on the person’s individual risk – such as a family history of disease, level of body fat and changes over time – they may opt for one of the obesity treatments above. Distinguishing people who don’t have illness from those who already have ongoing illness will enable personalised approaches to obesity prevention, management and treatment with more appropriate and cost-effective allocation of resources. <h2>What happens next?</h2> These new criteria for the diagnosis of clinical obesity will need to be adopted into national and international clinical practice guidelines and a range of obesity strategies. Once adopted, training health professionals and health service managers, and educating the general public, will be vital. Reframing the narrative of obesity may help eradicate misconceptions that contribute to stigma, including making false assumptions about the health status of people in larger bodies. A better understanding of the biology and health effects of obesity should also mean people in larger bodies are not blamed for their condition. People with obesity or who have larger bodies should expect personalised, evidence-based assessments and advice, free of stigma and blame.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/245164/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/louise-baur-5284">Louise Baur</a>, Professor, Discipline of Child and Adolescent Health, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>; <a href="https://theconversation.com/profiles/john-b-dixon-11630">John B. Dixon</a>, Adjunct Professor, Iverson Health Innovation Research Institute, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/priya-sumithran-1529047">Priya Sumithran</a>, Head of the Obesity and Metabolic Medicine Group in the Department of Surgery, School of Translational Medicine, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a>, and <a href="https://theconversation.com/profiles/wendy-a-brown-1665">Wendy A. Brown</a>, Professor and Chair, Monash University Department of Surgery, School of Translational Medicine, Alfred Health, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/how-we-diagnose-and-define-obesity-is-set-to-change-heres-why-and-what-it-means-for-treatment-245164">original article</a>. </div>

Body

How to turn your gift-giving crisis into a Christmas miracle

Christmas is coming, and with it, the annual What do I get everyone?! panic. Every year it’s the same: endless debates about whether Dad really needs another tie, your sister’s mysterious aversion to gift cards, and the horrifying memory of that one time you gave your neighbour a single fruitcake. Let’s be honest – nobody wants a single fruitcake. This year, skip the stress and let <a href="http://www.hamperworld.com.au/" target="_blank" rel="noopener">Hamper World</a> turn your gift-giving crisis into a Christmas miracle. Hamper World has been the secret Santa we all need for over 25 years, crafting stunning gift hampers packed with the best Australian-made goodies. We’re talking premium wines, gourmet snacks, fancy chocolates and artisanal treats that taste like they were made by elves with Michelin stars. It’s the kind of stuff that makes people’s eyes light up before they’ve even finished unwrapping it. <img src="https://oversixtydev.blob.core.windows.net/media/2024/12/IMG_0313_1280.jpg" alt="" width="1280" height="831" /> The beauty of these hampers is that they don’t just scream thoughtful gift. They also whisper, I didn’t just pick this up on the way here. Whether you’re shopping for family, friends, co-workers or that one random person who showed up for Christmas lunch (we all have one), there’s a hamper that’ll fit the bill – and make you look like a gifting genius in the process. Now, here’s the kicker: these hampers aren’t just packed with amazing stuff; they’re also doing some serious good. Every item is sourced from Australian producers, so your Christmas cheer is supporting local farmers, chocolatiers and small businesses. It’s basically like giving two gifts in one: one to your loved one, and one to Australia’s economy. Take that, Santa. <img src="https://oversixtydev.blob.core.windows.net/media/2024/12/21737A_1280_3.jpg" alt="" width="1280" height="720" /> And don’t get us started on delivery. You know that classic Christmas movie moment where the hero races through the snow (or, in our case, the scorching summer heat), trying to deliver the perfect gift? You don’t need that drama. Hamper World ships all over Australia, making sure your gift arrives looking as festive and fabulous as it did when it left. Whether it’s bound for a city penthouse or a bush retreat, your hamper will get there on time and looking sharp. But the real magic is in the presentation. Hamper World wraps these beauties up like they belong on the cover of a gourmet magazine. No need for awkward DIY attempts at gift wrapping that end with you covered in tape and regret. Just order, sit back and bask in the glory of being the best gift-giver in the history of your family. <img src="https://oversixtydev.blob.core.windows.net/media/2024/12/IMG_0321_1280.jpg" alt="" width="1280" height="831" /> Christmas hampers are also a great solution for those tricky situations. Got a boss who already has everything? Boom, corporate hamper. Want to thank your neighbours for putting up with your late-night karaoke sessions? Sweet treats hamper, done. And don’t forget to treat yourself – after all, nothing says Merry Christmas to me like a hamper full of wine and cheese. So, this Christmas, skip the socks, the scented candles and the questionable DIY projects. Head over to <a href="http://www.hamperworld.com.au" target="_blank" rel="noopener">www.hamperworld.com.au</a> or call 1800 566 433 and let Hamper World handle the heavy lifting. Because the only thing better than giving the perfect gift is doing it without breaking a sweat – and maybe even snagging a 10% gift card if you order early. Now that’s the holiday spirit. Images: Supplied This is a sponsored article produced in partnership with Hamper World

Food & Wine

What is ‘health at every size’ lifestyle counselling? How does it compare with weight-focused treatments?

<div class="theconversation-article-body"><a href="https://theconversation.com/profiles/clare-collins-7316">Clare Collins</a>, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a>; <a href="https://theconversation.com/profiles/erin-clarke-1314081">Erin Clarke</a>, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a>; <a href="https://theconversation.com/profiles/jordan-stanford-1631336">Jordan Stanford</a>, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a>, and <a href="https://theconversation.com/profiles/maria-gomez-martin-1218567">María Gómez Martín</a>, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a> Health at every size (or HAES) is a lifestyle counselling approach that promotes mindful eating and lifestyle behaviours to pursue health and wellness, without focusing on weight loss. Weight loss is seen as a <a href="https://www1.racgp.org.au/newsgp/clinical/understanding-the-%E2%80%98health-at-every-size%E2%80%99-paradigm">beneficial side effect</a>, rather than a goal. The <a href="https://www.sizeinclusivehealth.org.au/What-is-HAES">Association for Size Diversity and Health</a> first developed the approach in 2003 and revised it in 2013 and 2024. Its current <a href="https://asdah.org/haes/">core principles</a> promote: <ul> <li>minimising weight discrimination</li> <li>encouraging body acceptance</li> <li>intuitive eating</li> <li>enjoyable physical activities.</li> </ul> It also aims to address <a href="https://theobesitycollective.org.au/our-work/#weight-stigma-awareness">stigma and discrimination</a> that people in larger bodies may experience when seeking medical care. Internationally, a <a href="https://asdah.org/listing/">range of health professionals</a> have incorporated the HAES approach into their treatment and services. Some organisations, such as <a href="https://obesitycanada.ca/guidelines/nutrition/">Obesity Canada</a>, have included HAES in their <a href="https://pubmed.ncbi.nlm.nih.gov/32753461/">guidelines for obesity treatment</a>. <h2>How does it compare with weight-focused treatments?</h2> We conducted a <a href="https://pubmed.ncbi.nlm.nih.gov/38563692/">systematic review and meta-analysis</a> of all the research studies published until November 2022 that had used HAES-based programs. Across 19 scientific papers, we compared the outcomes of people living in larger bodies who used HAES-based programs <a href="https://pubmed.ncbi.nlm.nih.gov/38563692/">with</a>: <ul> <li>conventional weight loss programs (six studies)</li> <li>people on waiting lists receiving no treatment at all (six studies)</li> <li>groups where people received weekly social support in groups (four studies).</li> </ul> We evaluated the program’s impact on appetite, weight, physical health measurements including cholesterol and blood pressure, and also wellbeing and mental health. Our analysis found HAES interventions were beneficial in reducing susceptibility to hunger more than other approaches, meaning people had less subjective perceptions of hunger or eating in response to emotions. However, compared to control interventions, HAES did not show superior results for improving any other physical health outcome – weight loss, blood cholesterol levels, blood pressure – or wellbeing or mental health outcomes. Given the results to date, the choice about whether to use a HAES-based approach (or not) will depend on each person’s preference, needs and goals. <h2>Don’t get your health advice from influencers</h2> While HAES has been used in clinical practice for many years, some United States and Canadian anti-diet practitioner’s motives have been scrutinised because of their links <a href="https://www.washingtonpost.com/wellness/2024/04/03/diet-culture-nutrition-influencers-general-mills-processed-food/">with processed food companies</a>. The spotlight was put on the <a href="https://nutritionbycarrie.com/2024/04/washington-post-dietitians.html">very small number</a> of dietitian “influencers” (roughly 20 from a membership of more than 80,000 dietitians in the US and Canada) promoting “eat what you feel like” and discouraging people from making weight loss attempts, under the banner of HAES. They failed to mention they were being paid to promote products sold by food, beverage or supplement companies. US <a href="https://nutritionbycarrie.com/2024/04/washington-post-dietitians.html">author and dietitian Carrie Dennet</a> urges people to not look to influencers for health advice. Instead, seek non-judgemental health care from your GP. <h2>What might treatment look like?</h2> When improving your health is a treatment goal, a good place to start your journey is to have a health check-up with your doctor, as well as to assess your relationship with food. A healthy relationship with food means being able to eat appropriate amounts and variety of foods to meet your nutritional, health and wellbeing goals. This might include strategies such as: <ul> <li>keeping a <a href="https://theconversation.com/what-does-having-a-good-relationship-with-food-mean-4-ways-to-know-if-youve-got-one-202622">food mood diary</a></li> <li>reflecting on factors that influence your eating</li> <li>practising <a href="https://theconversation.com/thinking-youre-on-a-diet-is-half-the-problem-heres-how-to-be-a-mindful-eater-99207">mindful eating</a></li> <li>learning about nutrient needs</li> <li>focusing on food enjoyment and the pleasure that comes from preparing, sharing and eating with others.</li> </ul> If you need more help to develop this, ask your doctor to refer you to a health practitioner who can assist. <h2>What if your goal is weight loss?</h2> When it comes to medical nutrition therapy to treat weight-related health conditions, such as high blood pressure and type 2 diabetes, the approach will depend on individual needs and expectations. Broadly, there are three graded energy intake target levels: <ol> <li> a reduced-energy diet where the goal is to lower energy intake by 2,000 to 4,000 kilojoules (kJ) per day by identifying food substitutions, like swapping soft drinks and other sugar-sweetened drinks for zero or diet versions or water. </li> <li> a <a href="https://theconversation.com/health-check-whats-the-best-diet-for-weight-loss-21557">low-energy diet</a>, which uses an energy intake goal in the range of 4,200-5,000 kJ, up to 7,000 kJ per day depending on an individual’s energy expenditure. </li> <li> the most restricted regime is a <a href="https://theconversation.com/health-check-whats-the-best-diet-for-weight-loss-21557">very low-energy diet</a>, has an energy intake target less than 2,500 kJ/day, achieved using formulated meal replacement products. </li> </ol> The aim of a <a href="https://theconversation.com/health-check-whats-the-best-diet-for-weight-loss-21557">very low-energy diet</a> is to facilitate rapid weight loss when this is essential to improve health acutely such as poorly controlled type 2 diabetes. Such a diet should be used under supervision by your doctor and dietitian. When selecting an initial <a href="https://theconversation.com/health-check-whats-the-best-diet-for-weight-loss-21557">strategy</a>, seek a balance between energy intake goals and your ability to stick to it. Your approach may change over time as your health needs change. If you need personalised nutrition advice, ask for a referral to an accredited practising dietitian. The <a href="https://member.dietitiansaustralia.org.au/Portal/Portal/Search-Directories/Find-a-Dietitian.aspx">register of service providers though Dietitians Australia</a> allows you to view their expertise and location. Regardless of whether your practitioner uses a HAES approach or not, your health providers should always treat you with respect and address your personal health and wellbeing.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/234376/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/clare-collins-7316">Clare Collins</a>, Laureate Professor in Nutrition and Dietetics, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a>; <a href="https://theconversation.com/profiles/erin-clarke-1314081">Erin Clarke</a>, Postdoctoral Researcher, Nutrition and Dietetics, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a>; <a href="https://theconversation.com/profiles/jordan-stanford-1631336">Jordan Stanford</a>, Post Doctorate Fellow, Nutrition and Dietetics, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a>, and <a href="https://theconversation.com/profiles/maria-gomez-martin-1218567">María Gómez Martín</a>, Dietitian and early career researcher, <a href="https://theconversation.com/institutions/university-of-newcastle-1060">University of Newcastle</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-is-health-at-every-size-lifestyle-counselling-how-does-it-compare-with-weight-focused-treatments-234376">original article</a>. </div>

Body

"It's a miracle that I'm living": Victory dance for Aussie Paralympic superstar

Alexa Leary has emerged victorious at the Paralympic Games with a gold medal, three years after her life was changed from a horrific bike crash. In July 2021, Alexa was on a bike ride training as a triathlete when her front wheel clipped a bike in front of her, sending her flying form her bike at 70 kilometres an hour. Leary then underwent lifesaving surgery after the crash shattered her skull and left her unable to walk or talk, and spent 111 days in hospital. Now, the 23-year-old from the Sunshine Coast broke her own 100m freestyle world record on Thursday morning, walking away with a gold medal. "It's been a long, rough journey for me," Leary said at the Paris La Defense Arena. "It's a miracle that I'm living, and I'm walking and I'm talking. I was told that I never would three years ago, and I've just come so far." "I am so impressed with myself. I'm like, 'Lex, look how far you've actually come'. "It's not sad to talk about, but it's an emotional thing. My family is the reason why I'm here, and they're up there [in the stands] looking at me. Honestly, it's amazing." Alexa, who still struggles with memory problems and regulating her emotions, then shared how she kept at it in the pool as a recovery tool after her life-changing surgery, but found herself wanting to keep bettering her athletic ability. "I'm a passionate person," Alexa said after winning solo Paralympic gold. "When I want it, I'm going to go out and do it. I have to. "So I wanted to keep swimming for recovery. But I was like, 'Nah, I'm more than that!'." Alexa's parents, Belinda and Russ, watched their daughter's extraordinary win from the sidelines, reflecting on the haunting memories of Alexa's journey in hospital and how she came out the other side. Russ said, "I reckon she wanted that [gold medal] in her belly for three years. She wanted it. She got it. Unbelievable." Belinda added, "She's the same girl [post-accident], but everything's heightened, but all she ever wanted was to show people that anything is possible." "And what she's been through over the last three years, her thing is with a TBI [traumatic brain injury] anything is possible." Image credits: Nine News

Caring

"Shockingly irresponsible": Elle Macpherson slammed for "holistic" cancer treatment

Elle Macpherson has been subjected to widespread backlash online after revealing she opted for a "holistic" cancer treatments. The 60-year-old supermodel has revealed in her book, Elle: Life, Lessons, and Learning to Trust Yourself, that at the age of 53, she was <a href="https://oversixty.com.au/health/caring/elle-macpherson-reveals-secret-battle-with-cancer" target="_blank" rel="noopener">diagnosed</a> with breast cancer following a lumpectomy. She went on to share how she shunned the advice of doctors who recommended a mastectomy with radiation, chemotherapy, hormone therapy, plus reconstruction of her breast to fight the illness, deciding to forge her own path of "holistic wellness" to beat the disease without the use on conventional medicines. Since going public with her decision, Macpherson has been slammed online, with other cancer sufferers saying her comments are irresponsible and dangerous. One person wrote on X, "This is shockingly irresponsible from Elle Macpherson. She was lucky that clearly the lumpectomy removed all the cancerous cells and it hadn't spread, but implying she 'cured' cancer holistically is reckless beyond belief." Another person said, "Going through my own breast cancer battle atm I wish I there was a 'holistic approach' but there’s not... What I do have is different options & I’ll take whatever treatments both my oncologist’s offer me to ensure I live a longer life to be with my husband and kids." A third person added, "A lumpectomy isn't holistic, and she wouldn't have even known about the cancer 'to treat holistically' had she not gone the conventional medical route in the first place." Many took aim at the dangerous rhetoric, with one person saying, "There is real toxic wellness/positivity culture out there at the moment that is both unnerving and dangerous," while another added, "As a survivor, I am absolutely livid. This nonsense costs lives." Image credits: Instagram

Caring

Miracle update on baby boy scalded in public park

The mother of the nine-month-old boy who was scalded in a Brisbane park has shared a positive update on his condition as he awaits his third surgery. Baby Luka and his mother were enjoying the sun in Hanlon Park on August 27th when a stranger approached and poured boiling hot coffee over the baby boy. The nine-month-old was rushed to hospital, while the man accused of the attack remains at large. On Monday, Luka's mother shared that her son is up and walking again for the first time since the attack ahead of a third surgery that she hoped would deliver “more information about the next steps”. “Luka has been incredibly resilient. He’s up and about, walking and causing chaos. He is such a strong little boy and we are so so proud of him,” she said. The woman also confirmed that Luka suffered serious burns, with those under his neck and chest likely to scar, as the prospect of a skin graft has been raised by doctors. She said she had been "blown away" by the support she and her family had received through a GoFundMe campaign set up to pay for Luka's medical expenses. "This GoFundMe will be able to support Luka with all of his ongoing care needs which is truly a weight lifted off our shoulders," the woman said. “Not only that it will also support myself, my family, and ongoing mental health, given the nature of the event this will be an extremely long journey ahead for us all.” The fundraiser, that had a goal of just $5,000, surpassed $110,000 on Monday. Police earlier described the man they wish to speak to in connection to the attack as between 30-40 years old, of a proportionate build, with tanned skin. He was wearing a black hat, glasses, a shirt and shorts at the time Luka was burned. Image credits: 9News / Facebook

Caring

What is type 1.5 diabetes? It’s a bit like type 1 and a bit like type 2 – but it’s often misdiagnosed

<div class="theconversation-article-body"> <a href="https://theconversation.com/profiles/emily-burch-438717">Emily Burch</a>, <a href="https://theconversation.com/institutions/southern-cross-university-1160">Southern Cross University</a> and <a href="https://theconversation.com/profiles/lauren-ball-14718">Lauren Ball</a>, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a> While you’re likely familiar with type 1 and type 2 diabetes, you’ve probably heard less about type 1.5 diabetes. Also known as latent autoimmune diabetes in adults (LADA), type 1.5 diabetes has features of <a href="https://diabetesjournals.org/diabetes/article/69/10/2037/16062/Management-of-Latent-Autoimmune-Diabetes-in-Adults">both type 1 and type 2 diabetes</a>. More people became aware of this condition after <a href="https://www.imdb.com/name/nm0004726/">Lance Bass</a>, best known for his role in the iconic American pop band NSYNC, <a href="https://www.foxnews.com/health/pop-singer-lance-bass-type-1-5-diabetes-know-disease">recently revealed</a> he has it. So, what is type 1.5 diabetes? And how is it diagnosed and treated? <h2>There are several types of diabetes</h2> Diabetes mellitus is a group of conditions that arise when the levels of glucose (sugar) in our blood are higher than normal. There are actually <a href="https://diabetesjournals.org/care/article/37/Supplement_1/S81/37753/Diagnosis-and-Classification-of-Diabetes-Mellitus">more than ten types</a> of diabetes, but the <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01301-6/fulltext">most common</a> are type 1 and type 2. Type 1 diabetes is an <a href="https://diabetesjournals.org/care/article/44/11/2589/138492/The-Management-of-Type-1-Diabetes-in-Adults-A">autoimmune condition</a> where the body’s immune system attacks and destroys the cells in the pancreas that make the hormone insulin. This leads to very little or no insulin production. Insulin is important for moving glucose from the blood into our cells to be used for energy, which is why people with type 1 diabetes need <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995794/">insulin medication daily</a>. Type 1 diabetes usually <a href="https://www.nature.com/articles/s41390-024-03107-5">appears</a> in children or young adults. Type 2 diabetes is not an autoimmune condition. Rather, it happens when the body’s cells become resistant to insulin over time, and the pancreas is no longer able to make enough insulin to <a href="https://diabetesjournals.org/care/article/47/Supplement_1/S20/153954/2-Diagnosis-and-Classification-of-Diabetes">overcome this resistance</a>. Unlike type 1 diabetes, people with type 2 diabetes still produce some insulin. Type 2 is more common in adults but is <a href="https://www.sciencedirect.com/science/article/abs/pii/S1871402121002733">increasingly</a> seen in children and young people. Management <a href="https://www.racgp.org.au/getattachment/41fee8dc-7f97-4f87-9d90-b7af337af778/Management-of-type-2-diabetes-A-handbook-for-general-practice.aspx">can include</a> behavioural changes such as nutrition and physical activity, as well as oral medications and insulin therapy. <h2>How does type 1.5 diabetes differ from types 1 and 2?</h2> Like type 1 diabetes, type 1.5 occurs when the immune system attacks the pancreas cells that make insulin. But people with type 1.5 often don’t need insulin <a href="https://diabetesjournals.org/diabetes/article/69/10/2037/16062/Management-of-Latent-Autoimmune-Diabetes-in-Adults">immediately</a> because their condition develops more slowly. Most people with type 1.5 diabetes will need to use insulin within <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111528/">five years</a> of diagnosis, while those with type 1 typically require it from diagnosis. Type 1.5 diabetes is usually diagnosed in people <a href="https://diabetesjournals.org/diabetes/article/69/10/2037/16062/Management-of-Latent-Autoimmune-Diabetes-in-Adults">over 30</a>, likely due to the slow progressing nature of the condition. This is older than the typical age for type 1 diabetes but younger than the usual diagnosis age for type 2. Type 1.5 diabetes shares <a href="https://www.nature.com/articles/nrendo.2017.99">genetic and autoimmune risk factors</a> with type 1 diabetes such as specific gene variants. However, evidence has also shown it may be influenced by lifestyle factors such as <a href="https://pubmed.ncbi.nlm.nih.gov/29589073/">obesity</a> and <a href="https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2019.00320/full">physical inactivity</a> which are more commonly associated with type 2 diabetes. <h2>What are the symptoms, and how is it treated?</h2> The symptoms of type 1.5 diabetes are highly variable between people. Some have no symptoms at all. But generally, people may experience the following <a href="https://www.ncbi.nlm.nih.gov/books/NBK557897/">symptoms</a>: <ul> <li>increased thirst</li> <li>frequent urination</li> <li>fatigue</li> <li>blurred vision</li> <li>unintentional weight loss.</li> </ul> Typically, type 1.5 diabetes is <a href="https://diabetesjournals.org/diabetes/article/69/10/2037/16062/Management-of-Latent-Autoimmune-Diabetes-in-Adults">initially treated</a> with oral medications to keep blood glucose levels in normal range. Depending on their glucose control and the medication they are using, people with type 1.5 diabetes may need to monitor their blood glucose levels regularly throughout the day. When average blood glucose levels increase beyond normal range even with oral medications, treatment may progress to insulin. However, there are <a href="https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.959011/full">no universally accepted</a> management or treatment strategies for type 1.5 diabetes. <h2>Type 1.5 diabetes is often misdiagnosed</h2> Lance Bass said he was initially diagnosed with <a href="https://www.healthline.com/health-news/lance-bass-misdiagnosed-diabetes">type 2 diabetes</a>, but later learned he actually has type 1.5 diabetes. This is <a href="https://journals.lww.com/jaanp/abstract/2009/03000/latent_autoimmune_diabetes_of_adulthood__lada___an.4.aspx">not entirely uncommon</a>. Estimates suggest type 1.5 diabetes is misdiagnosed as type 2 diabetes <a href="https://www.sciencedirect.com/science/article/abs/pii/S1043276018301292">5–10% of the time</a>. There are a few possible reasons for this. First, accurately diagnosing type 1.5 diabetes, and distinguishing it from other types of diabetes, requires special <a href="https://journals.lww.com/jaanp/abstract/2009/03000/latent_autoimmune_diabetes_of_adulthood__lada___an.4.aspx">antibody tests</a> (a type of blood test) to detect autoimmune markers. Not all health-care professionals necessarily order these tests routinely, either due to cost concerns or because they may not consider them. Second, type 1.5 diabetes is commonly found in adults, so doctors might wrongly assume a person has developed type 2 diabetes, which is more common in this age group (whereas type 1 diabetes usually affects children and young adults). Third, people with <a href="https://diabetesjournals.org/diabetes/article/69/10/2037/16062/Management-of-Latent-Autoimmune-Diabetes-in-Adults">type 1.5 diabetes</a> often initially make enough insulin in the body to manage their blood glucose levels without needing to start insulin medication. This can make their condition appear like type 2 diabetes, where people also produce some insulin. Finally, because type 1.5 diabetes has <a href="https://www.ncbi.nlm.nih.gov/books/NBK557897/">symptoms</a> that are similar to type 2 diabetes, it may initially be treated as type 2. <h2>We’re still learning about type 1.5</h2> Compared with type 1 and type 2 diabetes, there has been much less research on how common type 1.5 diabetes is, especially in <a href="https://www.sciencedirect.com/science/article/abs/pii/S1043276018301292">non-European populations</a>. In 2023, it was estimated type 1.5 diabetes represented <a href="https://pubmed.ncbi.nlm.nih.gov/37428296/">8.9%</a> of all diabetes cases, which is similar to type 1. However, we need more research to get accurate numbers. Overall, there has been a limited awareness of type 1.5 diabetes and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683931/">unclear diagnostic criteria</a> which have slowed down our understanding of this condition. A misdiagnosis can be stressful and confusing. For people with type 1.5 diabetes, being misdiagnosed with type 2 diabetes might mean they don’t get the insulin they need in a timely manner. This can lead to worsening health and a greater likelihood of complications down the road. Getting the right diagnosis helps people receive the most appropriate treatment, save money, and reduce <a href="https://diabetesjournals.org/diabetes/article/73/Supplement_1/55-OR/155112/55-OR-Diabetes-Distress-among-Persons-Living-with">diabetes distress</a>. If you’re experiencing symptoms you think may indicate diabetes, or feel unsure about a diagnosis you’ve already received, monitor your symptoms and chat with your doctor.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/237041/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/emily-burch-438717">Emily Burch</a>, Accredited Practising Dietitian and Lecturer, <a href="https://theconversation.com/institutions/southern-cross-university-1160">Southern Cross University</a> and <a href="https://theconversation.com/profiles/lauren-ball-14718">Lauren Ball</a>, Professor of Community Health and Wellbeing, <a href="https://theconversation.com/institutions/the-university-of-queensland-805">The University of Queensland</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-is-type-1-5-diabetes-its-a-bit-like-type-1-and-a-bit-like-type-2-but-its-often-misdiagnosed-237041">original article</a>. </div>

Body

Why IBD is so hard to treat – and how scientists are making progress

<div class="theconversation-article-body"> <a href="https://theconversation.com/profiles/falk-hildebrand-1490022">Falk Hildebrand</a>, <a href="https://theconversation.com/institutions/quadram-institute-5557">Quadram Institute</a>; <a href="https://theconversation.com/profiles/katarzyna-sidorczuk-1490026">Katarzyna Sidorczuk</a>, <a href="https://theconversation.com/institutions/quadram-institute-5557">Quadram Institute</a>, and <a href="https://theconversation.com/profiles/wing-koon-1490274">Wing Koon</a>, <a href="https://theconversation.com/institutions/quadram-institute-5557">Quadram Institute</a> Inflammatory bowel disease (IBD) is a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478758/">life altering</a> chronic illness that is <a href="https://bmjopen.bmj.com/content/13/3/e065186">rising dramatically globally</a>. It is stubbornly difficult to treat, and many people find the treatments we have just don’t work for them. Over the last 30 years, there has been almost a 50% increase in cases – now affecting around 5 million people. Not to be confused with irritable bowel syndrome (IBS) which is a condition that affects the digestive system, IBD is more serious. It is the term for two severe illnesses called <a href="https://www.nhs.uk/conditions/crohns-disease/">Crohn’s disease</a> and <a href="https://www.nhs.uk/conditions/ulcerative-colitis/">ulcerative colitis</a>. More women are <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958616/#:%7E:text=Male%20predominance%20in%20IBD.,%2C%202.32%3A1%20in%20CD.">diagnosed with Crohn’s disease</a> while more men are affected by ulcerative colitis. People with IBD can experience a variety of <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106026/">symptoms</a>, ranging from diarrhoea and blood in the stool, to weight loss and belly aches. On paper, this may sound no worse than mild food poisoning, however, this is no normal stomach upset. Experiences are often extreme; people with IBD can suffer excruciating pain and in some cases, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963331/">require surgery</a> to remove parts of the bowel. This is done by redirecting the bowel to a hole in the abdomen, where faeces are collected in a <a href="https://www.nhs.uk/conditions/colostomy/">colostomy bag</a>. However, we still don’t fully understand the cause of IBD. <h2>The impact of inflammation</h2> The main symptom of IBD is excessive and uncontrolled <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805548/">inflammation</a> – normally a sign of the body fighting off an infection. Although inflammation is an important aspect of our immune system, in IBD it is happening when the body is not under attack. Since we don’t know what causes this over-the-top reaction, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720971/">treatments</a> are limited to managing the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964397/">derailed immune system</a>. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373857/">Inflammation is controlled</a> by cell signalling. Our cells detect bacteria using receptors that attach to parts of bacteria. This activates the receptor, causing it to send a signal to proteins, and each protein sends on more signals, creating a signal cascade. This is what tells the body it’s under attack. Many treatments follow the strategy of intercepting signals and preventing the signal cascade from starting. However, they are <a href="https://journals.lww.com/co-gastroenterology/abstract/2022/07000/management_of_refractory_inflammatory_bowel.6.aspx">not effective</a> for many people. Scientists are trying to target a different protein network, called <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924159/">NOD2</a>, that often goes haywire in people with IBD but is not targeted by current treatments. A protein, called <a href="https://www.frontiersin.org/articles/10.3389/fphar.2021.650403/full">RIPK2</a>, seems like a promising target since it is <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939834/">only found</a> in this network. Researchers from the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485824/">European Molecular Biology Laboratory</a> are investigating its structure to help scientists design a new medication that will block the signals from this protein. <h2>Importance of the microbiome</h2> Another inspiration for new treatments comes from the bacteria residing in our guts. This community of bacteria, called the gut microbiome, has been associated with <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314516/">all sorts of health conditions</a> ranging from asthma to obesity. Gut bacteria work closely with our bodies and play a vital role in digesting food and managing our <a href="https://www.nature.com/articles/s41422-020-0332-7">immune system</a>. In a healthy person, there is a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143175/">fine balance</a> between gut bacteria and the immune system. Disruption of this balance can lead to disease, starting from minor discomfort to more severe, long-term conditions. Scientists are trying to understand how our bodies interact with gut bacteria, and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102608/">what changes</a> when people develop IBD. The gut microbiome is an ecosystem. Just like a forest has animals eating different things, microbes can form a <a href="https://www.frontiersin.org/articles/10.3389/fevo.2019.00153/full">food web</a>. Some bacteria will use up one type of food, while others feed off other foods. Some rely on the waste of other bacteria after they’ve eaten. It is now believed that disruption to the gut microbiome is a characteristic of IBD and contributes to its development and progression. It’s a chicken and egg situation. Is there a change in the bacteria and food web that alters our bodies? Or does something else in the body, like our immune system, change the food web, subsequently limiting which bacteria can grow? Scientists aren’t sure of the answer. Instead of trying to figure out what happens first, a team at the <a href="https://www.nature.com/articles/s41467-023-42112-w">Hudson Institute of Medical Research</a> in Australia have focused on investigating which interactions in the food web are the most affected in IBD. This could help scientists to prioritise certain gut bacteria, or their food source, to restore the balance in the microbiome and improve patients’ symptoms. Hopefully, this specialised targeting of the microbiome will lead to more effective and longer lasting treatments. Although we have a long way to go before these ideas for treatments can become a reality, it is a step in the right direction. Targeting a new signalling pathway will hopefully control the inflammation in more patients. And studying the microbiome may reveal how we can reverse changes associated with IBD. Since they are key features of IBD, these developments could allow doctors to stop the disease in the early stages and reduce complications.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/218307/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/falk-hildebrand-1490022">Falk Hildebrand</a>, Researcher in Bioinformatician, <a href="https://theconversation.com/institutions/quadram-institute-5557">Quadram Institute</a>; <a href="https://theconversation.com/profiles/katarzyna-sidorczuk-1490026">Katarzyna Sidorczuk</a>, Research Scientist in Metagenomics, <a href="https://theconversation.com/institutions/quadram-institute-5557">Quadram Institute</a>, and <a href="https://theconversation.com/profiles/wing-koon-1490274">Wing Koon</a>, PhD student in Bioinformatics, <a href="https://theconversation.com/institutions/quadram-institute-5557">Quadram Institute</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/why-ibd-is-so-hard-to-treat-and-how-scientists-are-making-progress-218307">original article</a>. </div>

Body

The ultimate treatment to transform your curls

Every curly-haired girl knows the struggle of having to carry around multiple hair products to manage their curls. Anti-frizz serums, leave-in conditioners, curl cream and heat protection spray, are a few of the essentials that most curly hair girls can't live without, but what if there was a product that could do it all? Revlon's UniqOne Curls treatment is the perfect solution, and as someone who struggles with finding a curl treatment that doesn't leave my curls stringy or puffy, the treatment has become an essential part of my routine. The treatment boasts ten different benefits including: <ol> <li>Deeply nourishes and repairs damaged curls</li> <li>Enhances long-lasting natural curl definition </li> <li>96H frizz control </li> <li>Elasticity and bounce </li> <li>Provides lightweight, clean hold </li> <li>Conditions and detangles</li> <li>Heat protection </li> <li>Boosts shine </li> <li>Helps prevent split ends </li> <li>Softness and manageability</li> </ol> Yes, those are some big statements, but after my first use I could already see some of the benefits, especially as someone with fine, curly hair. I found that my hair was less frizzy and puffy and my curls were a lot more defined, even a few days after I initially applied it. I also loved the slight sweet and fruity scent that wasn't too overpowering. My hair was also easier to manage and style as it wasn't as tangled and despite the gel-like texture of the product, it didn't weigh down my fine hair or leave it feeling greasy. I found that the best way to use the product is to use it on damp hair. I like to pump the product onto the palm of my hand (approx. 5-12 times depending on the thickness and length of your hair) and then rubbing it in my hands, before applying it onto my hair on layered sections to ensure even distribution. I then detangle my hair with a wide tooth comb before scrunching my hair with my hands to ensure even curl clumps. I normally blow dry my hair, but it you have extra time on your hands, you can leave it to air dry. The product retails for $24.95 at <a href="https://www.ozhairandbeauty.com/products/revlon-professional-uniq-one-all-in-one-curls-treatment-230ml?currency=AUD&variant=40267971428424" target="_blank" rel="noopener">Oz Hair and Beauty</a> Images: Supplied

Beauty & Style

“Miracle”: 1-year-old baby survives two days beside highway during hurricane

A one-year-old baby has been found alive on the side of a highway after surviving two days of dangerous hurricane conditions between the Texas and Louisiana border in the US. A truck driver spotted the one-year-old on a major highway, just a few kilometres where the boy's four-year-old brother was tragically found dead in a lake. The one-year-old had to survive stormy weather as Hurricane Beryl inundated the area with heavy rain and high winds, but was relatively unscathed when he was found. The truck driver recalled the moment he found the child to local news station KPLC, saying, "There was a little boy sitting down in the embankment there." "As I approached him, he smiled at me and then he started crying and walked toward me. Once he walked toward me, I grabbed his hand and he stopped crying at that point." Calcasieu Parish Sheriff Gary “Stitch” Guillory said the baby had a few insect bites, but otherwise seemed well. “This kid spent two days out in the weather on the side of the highway,” Guillory said while becoming emotional. “Thank God that trucker seen him. When you look at the video, here he was, you know, crawling toward the highway." “We look at this one-year-old as our miracle baby because he was still alive.” The children’s mother, 25-year-old Aaliyah Jack of Lake Charles, has been charged with failing to report a missing child, while the child's grandmother is fighting for custody of the infant. Image credits: News15

Caring

"A bit grim": Sam Neill shares cancer update

Actor Sam Neill has shared a heartbreaking update on his cancer journey, which he has said he will eventually succumb to. Last year, the 76-year-old revealed that he was battling rare blood cancer, angioimmunoblastic T-cell lymphoma. After undergoing chemotherapy that failed to work, Neill's doctor switched him to an anti-cancer drug which has put him in remission for more than 12 months. The treatment requires him to have infusions every two weeks, and while his condition is currently stable, the drug will eventually stop working. Speaking candidly to the Herald Sun about his condition, he said while he is maintaining a positive outlook, the gruelling treatment is impacting the way he lives his life. “It’s just meant that every second week it was a case of forget about the weekend because that would be a bit grim,” he explained of his treatment schedule. “But other than that, it’s great to be alive and working and in beautiful places, like York.” Last year, Sam insisted while he wasn’t afraid of death after battling the disease, he “would be annoyed” because he still has plenty he wants to achieve. “I’m prepared for that,” Neill said at the time, adding that while dying would be “annoying” he’s not “remotely afraid” of it. “The last thing I want is for people to obsess about the cancer thing because I’m not really interested in cancer," he added. "I’m not really interested in anything other than living.” Image credits: Matt Baron/BEI/Shutterstock Editorial

Caring

Taking too many medications can pose health risks. Here’s how to avoid them

<div class="theconversation-article-body"><a href="https://theconversation.com/profiles/caroline-sirois-1524891">Caroline Sirois</a>, <a href="https://theconversation.com/institutions/universite-laval-1407">Université Laval</a> When we see an older family member handling a bulky box of medications sorted by day of the week, we might stop and wonder, is it too much? How do all those pills interact? The fact is, as we get older we are more likely to develop different chronic illnesses that require us to take several different medications. This is known as polypharmacy. The concept applies to people taking five or more medications, but there are all sorts of <a href="https://doi.org/10.3390/pharmacy7030126">definitions with different thresholds</a> (for example, four, 10 or 15 medicines). I’m a pharmacist and pharmacoepidemiologist interested in polypharmacy and its impact on the population. The research I carry out with my team at the Faculty of Pharmacy at Université Laval focuses on the appropriate use of medication by older family members. We have published this <a href="https://doi.org/10.1093/ageing/afac244">study</a> on the perceptions of older adults, family carers and clinicians on the use of medication among persons over 65. <h2>Polypharmacy among older adults</h2> Polypharmacy is very common among older adults. In 2021, a quarter of persons over 65 in Canada were prescribed <a href="https://www.cihi.ca/en/drug-use-among-seniors-in-canada">more than ten different classes of medication</a>. In Québec, persons over 65 used an average of <a href="https://www.inspq.qc.ca/sites/default/files/publications/2679_portrait_polypharmacie_aines_quebecois.pdf">8.7 different drugs in 2016</a>, the latest year available for statistics. Is it a good idea to take so many drugs? According to <a href="https://journals.sagepub.com/doi/10.1177/07334648211069553">our study</a>, the vast majority of seniors and family caregivers would be willing to stop taking one or more medications if the doctor said it was possible, even though most are satisfied with their treatments, <a href="https://doi.org/10.1093/ageing/afac244">have confidence in their doctors</a> and feel that their doctors are taking care of them to the best of their ability. In the majority of cases, medicine prescribers are helping the person they are treating. Medications have a positive impact on health and are essential in many cases. But while the treatment of individual illnesses is often adequate, the whole package can sometimes become problematic. <h2>The risks of polypharmacy: 5 points to consider</h2> When we evaluate cases of polypharmacy, we find that the quality of treatment is often compromised when many medications are being taken. <ol> <li> Drug interactions: polypharmacy increases the risk of drugs interacting, which can lead to undesirable effects or reduce the effectiveness of treatments. </li> <li> A drug that has a positive effect on one illness may have a negative effect on another: what should you do if someone has both illnesses? </li> <li> The greater the number of drugs taken, the greater the risk of undesirable effects: for adults over 65, for example, there is an increased risk of confusion or falls, which have significant consequences. </li> <li> The more medications a person takes, the more likely they are to take a <a href="https://www.doi.org/10.1093/fampra/cmz060">potentially inappropriate medication</a>. For seniors, these drugs generally carry more risks than benefits. For example, benzodiazepines, medicine for anxiety or sleep, are the <a href="https://www.inspq.qc.ca/sites/default/files/publications/2575_utilisation_medicaments_potentiellement_inappropries_aines.pdf">most frequently used class</a> of medications. We want to reduce their use as much as possible <a href="https://www.canada.ca/en/health-canada/services/substance-use/controlled-illegal-drugs/benzodiazepines.html">to avoid negative impacts</a> such as confusion and increased risk of falls and car accidents, not to mention the risk of dependence and death. </li> <li> Finally, polypharmacy is associated with various adverse health effects, such as an <a href="https://www.doi.org/10.1007/s41999-021-00479-3">increase in frailty, hospital admissions and emergency room visits</a>. However, studies conducted to date have not always succeeded in isolating the effects specific to polypharmacy. As polypharmacy is more common among people with multiple illnesses, these illnesses may also contribute to the observed risks. </li> </ol> Polypharmacy is also a combination of medicines. There are almost as many as there are people. The risks of these different combinations can vary. For example, the risks associated with a combination of five potentially inappropriate drugs would certainly be different from those associated with blood pressure medication and vitamin supplements. Polypharmacy is therefore complex. <a href="https://doi.org/10.1186/s12911-021-01583-x">Our studies attempt to use artificial intelligence</a> to manage this complexity and identify combinations associated with negative impacts. There is still a lot to learn about polypharmacy and its impact on health. <h2>3 tips to avoid the risks associated with polypharmacy</h2> What can we do as a patient, or as a caregiver? <ol> <li> Ask questions: when you or someone close to you is prescribed a new treatment, be curious. What are the benefits of the medication? What are the possible side effects? Does this fit in with my treatment goals and values? How long should this treatment last? Are there any circumstances in which discontinuing it should be considered ? </li> <li> Keep your medicines up to date: make sure they are all still useful. Are there still any benefits to taking them? Are there any side effects? Are there any drug interactions? Would another treatment be better? Should the dose be reduced? </li> <li> Think about de-prescribing: this is an increasingly common clinical practice that involves stopping or reducing the dose of an inappropriate drug after consulting a health-care professional. It is a shared decision-making process that involves the patient, their family and health-care professionals. The <a href="https://www.deprescribingnetwork.ca">Canadian Medication Appropriateness and Deprescribing Network</a> is a world leader in this practice. It has compiled a number of tools for patients and clinicians. You can find them on their website and subscribe to the newsletter. </li> </ol> <h2>Benefits should outweigh the risks</h2> Medications are very useful for staying healthy. It’s not uncommon for us to have to take more medications as we age, but this shouldn’t be seen as a foregone conclusion. Every medication we take must have direct or future benefits that outweigh the risks associated with them. As with many other issues, when it comes to polypharmacy, the saying, “everything in moderation,” frequently applies.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/230612/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/caroline-sirois-1524891">Caroline Sirois</a>, Professor in Pharmacy, <a href="https://theconversation.com/institutions/universite-laval-1407">Université Laval</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/taking-too-many-medications-can-pose-health-risks-heres-how-to-avoid-them-230612">original article</a>. </div>

Body

Exercise, therapy and diet can all improve life during cancer treatment and boost survival. Here’s how

<div class="theconversation-article-body"> <a href="https://theconversation.com/profiles/rob-newton-12124">Rob Newton</a>, <a href="https://theconversation.com/institutions/edith-cowan-university-720">Edith Cowan University</a> With so many high-profile people <a href="https://www.theguardian.com/uk-news/2024/mar/23/cancer-charities-princess-of-wales-speaking-about-diagnosis">diagnosed with cancer</a> we are confronted with the stark reality the disease can strike any of us at any time. There are also reports certain cancers are <a href="https://www.cancer.org/research/acs-research-news/facts-and-figures-2024.html">increasing among younger people</a> in their 30s and 40s. On the positive side, medical treatments for cancer are advancing very rapidly. Survival rates are <a href="https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21763">improving greatly</a> and some cancers are now being managed more as <a href="https://www.cancer.org/cancer/survivorship/long-term-health-concerns/cancer-as-a-chronic-illness.html">long-term chronic diseases</a> rather than illnesses that will rapidly claim a patient’s life. The <a href="https://www.cancer.org/cancer/managing-cancer/treatment-types.html">mainstays of cancer treatment</a> remain surgery, chemotherapy, radiation therapy, immunotherapy, targeted therapy and hormone therapy. But there are other treatments and strategies – “adjunct” or supportive cancer care – that can have a powerful impact on a patient’s quality of life, survival and experience during cancer treatment. <h2>Keep moving if you can</h2> Physical exercise is now recognised as a <a href="https://www.exerciseismedicine.org/">medicine</a>. It can be tailored to the patient and their health issues to stimulate the body and build an internal environment where <a href="https://wchh.onlinelibrary.wiley.com/doi/full/10.1002/tre.884">cancer is less likely to flourish</a>. It does this in a number of ways. Exercise provides a strong stimulus to our immune system, increasing the number of cancer-fighting immune cells in our blood circulation and infusing these into the tumour tissue <a href="https://jitc.bmj.com/content/9/7/e001872">to identify and kill cancer cells</a>. Our skeletal muscles (those attached to bone for movement) release signalling molecules called <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288608/">myokines</a>. The larger the muscle mass, the more myokines are released – even when a person is at rest. However, during and immediately after bouts of exercise, a further surge of myokines is secreted into the bloodstream. Myokines attach to immune cells, stimulating them to be better “hunter-killers”. Myokines also signal directly to cancer cells <a href="https://www.sciencedirect.com/science/article/pii/S2095254623001175">slowing their growth and causing cell death</a>. Exercise can also greatly <a href="https://wchh.onlinelibrary.wiley.com/doi/full/10.1002/tre.884">reduce the side effects of cancer treatment</a> such as fatigue, muscle and bone loss, and fat gain. And it reduces the risk of <a href="https://doi.org/10.2337/diacare.27.7.1812">developing other chronic diseases</a> such as heart disease and type 2 diabetes. Exercise can maintain or improve quality of life and mental health <a href="https://www.hindawi.com/journals/tbj/2022/9921575/">for patients with cancer</a>. Emerging research evidence indicates exercise might increase the effectiveness of mainstream treatments such as <a href="https://aacrjournals.org/cancerres/article/81/19/4889/670308/Effects-of-Exercise-on-Cancer-Treatment-Efficacy-A">chemotherapy</a> and <a href="https://www.nature.com/articles/s41391-020-0245-z">radiation therapy</a>. Exercise is certainly essential for preparing the patient for any surgery to increase cardio-respiratory fitness, reduce systemic inflammation, and increase muscle mass, strength and physical function, and then <a href="https://www.jsams.org/article/S1440-2440(18)31270-2/fulltext">rehabilitating them after surgery</a>. These mechanisms explain why cancer patients who are physically active have much <a href="https://journals.lww.com/acsm-msse/fulltext/2019/06000/physical_activity_in_cancer_prevention_and.20.aspx">better survival outcomes</a> with the relative risk of death from cancer <a href="https://journals.lww.com/acsm-msse/fulltext/2019/06000/physical_activity_in_cancer_prevention_and.20.aspx">reduced by as much as 40–50%</a>. <h2>Mental health helps</h2> The second “tool” which has a major role in cancer management is <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016045/">psycho-oncology</a>. It involves the psychological, social, behavioural and emotional aspects of cancer for not only the patient but also their carers and family. The aim is to maintain or improve quality of life and mental health aspects such as emotional distress, anxiety, depression, sexual health, coping strategies, personal identity and relationships. Supporting quality of life and happiness is important on their own, but these barometers <a href="https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2024.1349880/full">can also impact</a> a patient’s physical health, response to exercise medicine, resilience to disease and to treatments. If a patient is highly distressed or anxious, their body can enter a flight or fight response. This creates an internal environment that is actually supportive of cancer progression <a href="https://www.cancer.gov/about-cancer/coping/feelings/stress-fact-sheet">through hormonal and inflammatory mechanisms</a>. So it’s essential their mental health is supported. <h2>Putting the good things in: diet</h2> A third therapy in the supportive cancer care toolbox is diet. A healthy diet <a href="https://www.cancer.org/cancer/survivorship/coping/nutrition/benefits.html">can support the body</a> to fight cancer and help it tolerate and recover from medical or surgical treatments. Inflammation provides a more fertile environment <a href="https://www.cancer.gov/news-events/cancer-currents-blog/2022/reducing-inflammation-to-treat-cancer">for cancer cells</a>. If a patient is overweight with excessive fat tissue then a diet to reduce fat which is also anti-inflammatory can be very helpful. This <a href="https://www.frontiersin.org/articles/10.3389/fnut.2021.709435/full">generally means</a> avoiding processed foods and eating predominantly fresh food, locally sourced and mostly plant based. Muscle loss is <a href="https://onlinelibrary.wiley.com/doi/10.1002/rco2.56">a side effect of all cancer treatments</a>. Resistance training exercise can help but people may need protein supplements or diet changes to make sure they get enough protein to build muscle. Older age and cancer treatments may reduce both the intake of protein and compromise absorption so <a href="https://www.sciencedirect.com/science/article/pii/S0261561421005422">supplementation may be indicated</a>. Depending on the cancer and treatment, some patients may require highly specialised diet therapy. Some cancers such as pancreatic, stomach, esophageal, and lung cancer can cause rapid and uncontrolled drops in body weight. This is called <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233663/">cachexia and needs careful management</a>. Other cancers and treatments such as hormone therapy can cause rapid weight gain. This also needs careful monitoring and guidance so that, when a patient is clear of cancer, they are not left with higher risks of other health problems such as cardiovascular disease and metabolic syndrome (a cluster of conditions that boost your risk of heart disease, stroke and type 2 diabetes). <h2>Working as a team</h2> These are three of the most powerful tools in the supportive care toolbox for people with cancer. None of them are “cures” for cancer, alone or together. But they can work in tandem with medical treatments to greatly improve outcomes for patients. If you or someone you care about has cancer, national and state cancer councils and cancer-specific organisations can provide support. For exercise medicine support it is best to consult with an <a href="https://www.essa.org.au/Public/Public/Consumer_Information/What_is_an_Accredited_Exercise_Physiologist_.aspx">accredited exercise physiologist</a>, for diet therapy an <a href="https://dietitiansaustralia.org.au/working-dietetics/standards-and-scope/role-accredited-practising-dietitian">accredited practising dietitian</a> and mental health support with a <a href="https://psychology.org.au/psychology/about-psychology/what-is-psychology">registered psychologist</a>. Some of these services are supported through Medicare on referral from a general practitioner. <hr /> For free and confidential cancer support call the <a href="https://www.cancer.org.au/support-and-services/cancer-council-13-11-20">Cancer Council</a> on 13 11 20.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/226720/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/rob-newton-12124">Rob Newton</a>, Professor of Exercise Medicine, <a href="https://theconversation.com/institutions/edith-cowan-university-720">Edith Cowan University</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/exercise-therapy-and-diet-can-all-improve-life-during-cancer-treatment-and-boost-survival-heres-how-226720">original article</a>. </div>

Caring

Doctor beats cancer using his own treatment

Australian doctor Richard Scolyer has been declared cancer free, thanks to a first-of-its-kind treatment he helped to develop. The 56-year-old professor, who has been recognised around for the world for his pioneering melanoma research, was diagnosed with aglioblastoma, a terminal kind of brain tumour, after suffering a seizure last June. After receiving his devastating diagnosis, the doctor agreed to be a "guinea pig" to undergo a world-first cancer treatment that he had a hand in developing. Now the world-leading pathologist and Australian of the Year has given a remarkable update, stating he is cancer free. “I had brain #MRI scan last Thursday looking for recurrent #glioblastoma (&/or treatment complications). I found out yesterday that there is still no sign of recurrence. I couldn’t be happier!!!!!” the professor shared on X, formerly known as Twitter. Before Dr Scolyer was diagnosed with cancer, he was fit and active, and had been hiking mountains in Poland with his wife. “I felt normal. I didn’t have any symptoms at all,” he told A Current Affair earlier this year. Just days after, he suffered a devastating seizure, and when he returned to Australia, underwent a series of tests which resulted in a diagnosis with glioblastoma – an aggressive and terminal form of brain cancer that would give him a average of 14 months to live. Teaming up with his friend and medical oncologist Georgina Long, Scolyer decided to undergo the new treatment, which came with a long list of risks. “No one knew what it was going to do, people were nervous because it could actually cause my life to end more quickly. But when you’re faced with certain death, it’s a no-brainer for me,” said Professor Scolyer, who also hoped the treatment would make a difference for other cancer patients. Dr Scolyer also underwent surgery to remove as much of his tumour as possible, and in April, he updated his social media followers to share that10 months after his diagnosis, his tumour had not returned. Speaking to ABC’s Australian Story at the time, Professor Scolyer said he was “blown away” by the results. “This is not what I expected. The average time to recurrence for the nasty type of brain cancer I’ve got is six months. So, to be out this far is amazing,” he said. Image credits: Instagram

Caring

Princess of Wales and King Charles: one in two people develop cancer during their lives – the diseases and treatments explained

<a href="https://theconversation.com/profiles/gavin-metcalf-1340598">Gavin Metcalf</a>, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a> The Princess of Wales released a <a href="https://x.com/KensingtonRoyal/status/1771235267837321694?s=20">moving video message</a> on March 22 to address speculation about her health. In it, the future queen disclosed that she’d been <a href="https://www.bbc.co.uk/news/health-68641710">diagnosed with cancer</a> following tests conducted after she underwent major abdominal surgery at a clinic in London in January. Catherine explained that she was undergoing “preventative chemotherapy” – but emphasised that her surgery had been successful, and that she was “well” and “getting stronger every day”. The message was the <a href="https://www.theguardian.com/uk-news/2024/mar/22/princess-kate-cancer-royal-family-health-annus-horribilis">second announcement</a> of a royal family cancer diagnosis in recent weeks. On February 5, Buckingham Palace <a href="https://www.royal.uk/a-statement-from-buckingham-palace-5Feb24">published a statement</a> that King Charles III had been diagnosed with an undisclosed form of <a href="https://www.bbc.co.uk/news/uk-68208157">cancer, unrelated</a> to the treatment he had been receiving for an enlarged prostate. <figure><iframe src="https://www.youtube.com/embed/3xzKooCaRXU?wmode=transparent&start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe></figure> The statement said that he had begun “regular treatments”. The king postponed all public-facing duties during his treatment, but <a href="https://www.bbc.co.uk/news/uk-68213383">reportedly continued</a> with his “constitutional role as head of state, including completing paperwork and holding private meetings”. Cancer is the <a href="https://www.who.int/news-room/fact-sheets/detail/cancer">leading cause of death</a> worldwide. <a href="https://www.nhs.uk/conditions/cancer/#:%7E:text=The%20cancerous%20cells%20can%20invade,of%20cancer%20during%20their%20lifetime.">One in two</a> people will develop some form of cancer in their lifetime – so the condition will affect almost every family. However, many cancers can be cured if, as appears to be the case with the king, the condition is <a href="https://www.bbc.co.uk/news/uk-68213383">detected early</a> and treated effectively. <h2>What is cancer?</h2> Our bodies are made up of more than 100 billion cells, and cancer typically starts with changes in a small group of cells – or even a single one. We have different cell types depending upon where in the body they are and the function that the cell has. The size, amount and function of each of these cells is normally tightly regulated by genes – groups of codes held within our DNA – that instruct cells how to grow and divide. However, changes (mutations) to DNA can alter the way cells grow and multiply – often forming a lump, or solid tumour. Cancers can also develop in blood cells, such as white blood cell cancer which is known as leukaemia. This type of cancer does not form solid tumours; instead, the cancer builds up in the blood or sometimes the marrow in the core of bones, where blood cells are produced. In all, there are <a href="https://www.cancerresearchuk.org/about-cancer/what-is-cancer/how-cancer-starts/types-of-cancer#:%7E:text=For%20example%2C%20nerves%20and%20muscles,of%20cell%20they%20start%20in.">more than 200</a> types of cancer, but all start with mutations in the DNA contained within each and every cell. <h2>What exactly are mutations?</h2> Think of your DNA as a big recipe book, and your genes as individual recipes for making different dishes. Mutations are smudges or missing words from this recipe that can result in key ingredients not being added into the mix. <figure><iframe src="https://www.youtube.com/embed/8BJ8_5Gyhg8?wmode=transparent&start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe></figure> Regardless of the type of cancer or the cells from which it develops, mutations in our genes can result in a cell no longer understanding its instructions. These mutations can happen by chance when dividing, but can also be the result of lifestyle choices such as <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141049/">smoking</a>, <a href="https://www.ndph.ox.ac.uk/news/new-genetic-study-confirms-that-alcohol-is-a-direct-cause-of-cancer#:%7E:text=These%20mutations%20both%20disrupt%20the,aldehyde%20dehydrogenase%202%20(ALDH2).">drinking</a>, and <a href="https://www.cancer.gov/about-cancer/causes-prevention/risk/obesity/physical-activity-fact-sheet">inactivity</a>. Research has found that in order for a normal cell to turn into a cancerous cell, anywhere from <a href="https://www.sanger.ac.uk/news_item/1-10-mutations-are-needed-drive-cancer-scientists-find/">one to ten different mutations</a> are normally required. <h2>How is cancer treated?</h2> Treatment options for cancer depend on a variety of factors, including where your cancer is, how large it is, and whether it has spread to other parts of the body. The main treatments for cancer include surgery, chemotherapy, and radiotherapy. Chemotherapy uses drugs to target and kill cells that are rapidly dividing in our bodies. This approach is effective at targeting fast-growing cells in various cancers – but also has negative side effects. It also targets healthy cells that rapidly divide, such as hair and the cells lining our digestive system. This can lead to commonly reported <a href="https://www.nhs.uk/conditions/chemotherapy/side-effects/">side-effects</a> such as hair loss, nausea and diarrhoea. <a href="https://www.cancerresearchuk.org/about-cancer/treatment/chemotherapy?gad_source=1&gclid=Cj0KCQjw-_mvBhDwARIsAA-Q0Q6tyQxTuBzU7vVD7SHjQ5dF-fRdqnL7S74-k5LXyTqODydsrPfJVsoaAkgyEALw_wcB&gclsrc=aw.ds">Chemotherapy</a> can be used both preventatively – as in the case of the princess – and therapeutically. <figure><iframe src="https://www.youtube.com/embed/FkZn5u3MIiY?wmode=transparent&start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe></figure> Preventative chemotherapy, also known as <a href="https://www.cancer.gov/publications/dictionaries/cancer-terms/def/adjuvant-therapy">adjuvant chemotherapy</a>, is given after surgery or other primary treatments to eliminate any remaining cancer cells in the body. It aims to reduce the risk of the cancer returning (known as recurrence). Therapeutic chemotherapy is used as a treatment option for cancer that has spread or is well established, such as advanced-stage cancers. <a href="https://www.cancerresearchuk.org/about-cancer/treatment/surgery/about">Surgery</a> involves the physical removal of cancerous tissues as well as nearby lymph nodes – small glands which act as filters in your body that cancers can spread through – to eliminate the tumour. Surgery is often used to remove localised cancers that haven’t spread throughout the body. <a href="https://www.cancerresearchuk.org/about-cancer/treatment/radiotherapy">Radiotherapy</a> uses high-energy radiation beams that are able to target specific areas where tumour cells are located to destroy or shrink the tumour. Radiotherapy can be applied externally or internally. Chemotherapy, surgery, and radiotherapy are often combined in cancer treatment to improve outcomes for patients. Thanks to developments in cancer research over the last 50 years, survival rates have improved greatly – although the rate of improvement has <a href="https://news.cancerresearchuk.org/2024/02/02/world-cancer-day-2024/#:%7E:text=Improvements%20in%20cancer%20survival%20have%20slowed%20in%20recent%20years&text=Survival%20increased%20three%20to%20five,consistently%20lags%20behind%20comparable%20countries.">slowed recently</a>. Cancer survival depends on various factors such as age – people under 40 have a <a href="https://www.cancer.gov/about-cancer/causes-prevention/risk/age">greater chance</a> of survival – overall health and fitness, as well as family history. <h2>What you should do</h2> Particular changes in your body or warning symptoms could indicate the presence of cancer. These include, but are not limited to: <ul> <li>Unexplained weight loss;</li> <li>Fatigue that doesn’t improve with rest;</li> <li>Changes in bowel or bladder habits;</li> <li>Persistent cough or coughing up blood;</li> <li>Difficulty swallowing;</li> <li>Persistent pain;</li> <li>Noticing lumps, such as in a breast or testicle.</li> </ul> The symptoms may not necessarily be the result of cancer. But it is important to get checked by a doctor if you notice anything out of the ordinary or have had persistent symptoms that don’t ease. Early detection and treatment can <a href="https://www.science.org/doi/full/10.1126/science.aay9040">significantly improve</a> outcomes for many types of cancer.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/226456/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/gavin-metcalf-1340598">Gavin Metcalf</a>, Cancer Biologist and Lecturer in Biomedical Science, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/princess-of-wales-and-king-charles-one-in-two-people-develop-cancer-during-their-lives-the-diseases-and-treatments-explained-226456">original article</a>.

Caring

What is minoxidil, the anti-balding hair growth treatment? Here’s what the science says

<a href="https://theconversation.com/profiles/jacinta-l-johnson-1441348">Jacinta L. Johnson</a>, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> and <a href="https://theconversation.com/profiles/kirsten-staff-1494356">Kirsten Staff</a>, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> Hair loss (also known as alopecia) often affects the scalp but can occur anywhere on the body. It’s very common and usually nothing to worry about; about <a href="https://www.sciencedirect.com/science/article/pii/S0022202X15525840">half of Australian men</a> show signs of visible baldness at age 50 and <a href="https://www.sciencedirect.com/science/article/pii/S0022202X15525840">over a quarter of Australian women</a> report hair thinning by the same age. It’s often genetic. But if you’ve noticed hair loss and are worried by it, see a GP or dermatologist for a diagnosis before trying any treatments. Products claiming to reverse hair loss are everywhere, but few have been scientifically tested for how well they work. One group of products that have actually been scientifically tested, however, are known as topical minoxidil products. These include products such as Regaine®. So, do they work? Here’s what the research evidence says, what you can realistically expect and what you need to know if you’re considering this treatment. <h2>What is minoxidil – and does it work?</h2> Topical minoxidil usually comes as a kind of foam or serum you apply to your scalp. It’s been approved by the <a href="https://www.tga.gov.au/">Therapeutic Goods Administration</a>, Australia’s regulatory authority for therapeutic goods, for the treatment of hereditary hair loss in males and females. Minoxidil is also available in tablet form, but this isn’t currently approved for hair loss (more on that later). So, is topical minoxidil effective? In short – yes, but the results vary widely from person to person, and it needs to be used consistently over several months to see results. Scientists don’t know exactly how minoxidil works. It may affect the different phases of the hair life cycle, thereby encouraging growth. It also <a href="https://www.tandfonline.com/doi/full/10.1080/09546634.2021.1945527?casa_token=KhIM_u0u8nwAAAAA:5njp_XE5cHhip454ycvU1p9p_t0VVzpjRu0ozDZ9YqNb04fmhmngWzYeiowZcG5UugLQkTVIzCcj7A">opens up blood vessels</a> near hair follicles. This increases blood flow, which in turn delivers more oxygen and nutrients to the hair. While minoxidil is unlikely to restore a full head of thick, lush, hair, it can slow down hair loss and can <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007628.pub4/full?highlightAbstract=minoxidil">stimulate regrowth</a>. It is the over-the-counter option with the most evidence. Two strengths are available: 5% and 2%. An analysis of randomised controlled trials found minoxidil applied to the scalp twice a day increased the number of hairs per square centimetre by <a href="https://pubmed.ncbi.nlm.nih.gov/28396101/">eight to 15 hairs</a>, with the higher strength treatment having a slightly greater effect. <h2>Can I use it for non-genetic balding?</h2> There are many causes of hair loss. The main cause in both males and females is a hereditary condition called androgenic alopecia. Although topical minoxidil is only approved for use in Australia for androgenic alopecia, there is some evidence it can also help in other conditions that cause hair loss. For example, it may hasten hair regrowth in patients who have lost hair due to <a href="https://www.jaad.org/article/S0190-9622(96)90500-9/abstract">chemotherapy</a>. Unfortunately, minoxidil is not effective when the hair follicle is gone, like after a burn injury. Although small studies have found promising results using minoxidil to promote hair growth on the face (for <a href="https://onlinelibrary.wiley.com/doi/epdf/10.1111/1346-8138.13312">beard</a> or <a href="https://pubmed.ncbi.nlm.nih.gov/24471459/">eyebrow</a> enhancement), topical minoxidil products are not currently approved for this use. More research is required. <h2>What else do I need to know?</h2> Minoxidil won’t work well for everyone. Early in treatment you might notice a temporary increase in <a href="https://pubmed.ncbi.nlm.nih.gov/22409453/">hair shedding</a>, as it alters the hair cycle to make way for new growth. Minoxidil needs to be trialled for three to six months to determine if it’s effective. And as it doesn’t cure hair loss, you must <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/jdv.14624?casa_token=P-zW7kDNRs8AAAAA%3AaUgUzxU7lbwBpg1BYPajOfXFhpb_mU5g_ounZ6GtjsLLkHO_AdVQ2Kf-8zZkW80ykBj3N_sOsyn392uc">continue</a> to use it each day to maintain the effect. If you stop, you will start losing the new hair growth <a href="https://www.nps.org.au/assets/medicines/1f8127a5-2a98-4013-a7c3-a53300feb0e5-reduced.pdf">within three to four months</a>. Minoxidil products may not be suitable for everyone. If you have any medical conditions or take any medications, you should speak with your doctor or pharmacist before using minoxidil products. It has not been tested for safety in <a href="https://www.nps.org.au/assets/medicines/1f8127a5-2a98-4013-a7c3-a53300feb0e5-reduced.pdf">people under 18, over 65, or those who are pregnant</a>. You can read the <a href="https://www.nps.org.au/medicine-finder/regaine-for-men-regular-strength-application">consumer medicines information sheet</a> for more information about using over-the-counter minoxidil products. Many people do not like to use minoxidil solution or foams long-term because they need to be applied everyday day, which can be inconvenient. Or they may notice side effects, such as scalp irritation and changes to hair texture. Some people <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/jdv.14624?casa_token=P-zW7kDNRs8AAAAA%3AaUgUzxU7lbwBpg1BYPajOfXFhpb_mU5g_ounZ6GtjsLLkHO_AdVQ2Kf-8zZkW80ykBj3N_sOsyn392uc">tolerate the foam products better</a> than the solution, as the solution contains more of a compound called propylene glycol (which can irritate the skin). <h2>What about the oral tablet form of minoxidil?</h2> Minoxidil is also available on prescription as an oral tablet. While traditionally used for high blood pressure, it has also been used as a treatment for hair loss. In 2020, a <a href="https://www.jaad.org/article/S0190-9622(20)32109-5/abstract">systematic review</a> identified 17 studies involving 634 patients using oral minoxidil for various hair loss conditions. The authors found oral minoxidil was effective and generally well tolerated in healthy people who were having trouble using the topical products. The review noted oral minoxidil may increase hair growth over the whole body and may cause heart-related side effects in some patients. More research is required. In Australia, oral minoxidil is available under the trade name <a href="https://www.nps.org.au/assets/medicines/df29e16f-6464-4652-ba1f-a53300fed275.pdf">Loniten</a>®. However, it is currently only approved for use in high blood pressure. When people seek a prescription treatment for a non-approved purpose, this is called “off-label” prescribing. Off-label prescribing of oral minoxidil, potentially for use in alopecia, may have contributed to <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170338/">shortages</a> of Loniten® tablets in recent years. This can reduce availability of this medicine for people who need it for high blood pressure.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/223736/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/jacinta-l-johnson-1441348">Jacinta L. Johnson</a>, Senior Lecturer in Pharmacy Practice, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> and <a href="https://theconversation.com/profiles/kirsten-staff-1494356">Kirsten Staff</a>, Senior Lecturer in Pharmacy, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-is-minoxidil-the-anti-balding-hair-growth-treatment-heres-what-the-science-says-223736">original article</a>. Image: Getty

Body

King Charles delivers heartfelt message amidst cancer treatment

In times of adversity, the power of unity and compassion shines through, and this sentiment has never been more evident than in the heartfelt message delivered by King Charles amidst his cancer treatment. As news of his diagnosis spread, an outpouring of support enveloped the King from all corners of the Commonwealth. His gratitude and appreciation for this unwavering kindness were palpable as he addressed the nations in a video message, unable to personally attend the 2024 Commonwealth Day celebrations due to his health. "I have been most deeply touched by your wonderfully kind and thoughtful good wishes for my health and, in return, can only continue to serve you, to the best of my ability, throughout the Commonwealth," he said. "My belief in our shared endeavours and in the potential of our people remains as sure and strong as it has ever been. I have no doubt that we will continue to support one another across the Commonwealth as, together, we continue this vital journey." The absence of the Princess of Wales, still in recovery from surgery, served as a reminder of the fragility of life and the importance of cherishing every moment with loved ones. In such moments, the strength of familial bonds and the support of a caring community become invaluable lifelines. As we celebrate the 75th anniversary of the Commonwealth, we reflect not only on its historical significance but also on its enduring relevance in today's world. The theme of "One Resilient Common Future: Transforming our Commonwealth" resonates deeply as we navigate the challenges of the modern age together. King Charles' words remind us of the interconnectedness of our shared humanity, transcending borders and differences. He likened the Commonwealth to the wiring of a house, where each nation contributes to the collective energy and strength that sustains us all: "As I have said before, the Commonwealth is like the wiring of a house, and its people, our energy and our ideas are the current that runs through those wires. Together and individually we are strengthened by sharing perspectives and experiences, and by offering and borrowing the myriad ways we have each tackled the challenges of our time. This is true both at the level of nations and, indeed, at the local level. We recognise today that our diversity is our greatest strength." In facing global challenges such as climate change, biodiversity loss and socioeconomic shifts, the importance of collaboration and cooperation cannot be overstated. King Charles eloquently underscored the power of diversity as our greatest strength, recognising that it is through our varied perspectives and experiences that we find innovative solutions to complex problems. <iframe title="YouTube video player" src="https://www.youtube.com/embed/lR6Z8ss_AW0?si=Gf8lGHmG-xnw9zCP" width="560" height="315" frameborder="0" allowfullscreen="allowfullscreen"></iframe> Image: Youtube

Caring

"Two little miracles": Wiggles star announces pregnancy

The Wiggles star Caterina Mete has announced that she is pregnant with twin girls. The journey to pregnancy has been a long one for the Red Wiggle, and she took to Instagram on Tuesday morning to share her experience. “I’m due later in the year, but I wanted to share this news with you now as I’ll be seeing many of you at the upcoming Wiggles shows, and as you can see, my girls are already starting to make an appearance,” the 43-year-old said. “My two little miracles are the result of a long journey through IVF and an anonymous donor from my fertility clinic. I’m so excited for the adventure ahead, and I can’t wait to be a mum. “I look forward to sharing more with you as I continue on this incredible journey.” Fellow Wiggle members flooded her comments with congratulatory messages. “Absolutely delighted by your amazing news! Your Wiggles family is with you on this magical journey," wrote Blue Wiggle Anthony Field. “Big congratulations Caterina! I have no doubt you'll be an incredible mum. Can't wait to share in all the love and joy your little ones will bring to our Wiggles family!” Yellow Wiggle Tsehay Hawkins added. <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/reel/C30kIMivqCB/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/C30kIMivqCB/?utm_source=ig_embed&utm_campaign=loading" target="_blank" rel="noopener">A post shared by Caterina Wiggle (@caterina.wiggle)</a> </div> </blockquote> “Double happy!!!! Congratulations Caterina on such fantastic news. Love from all of us!!!” wrote Purple Wiggle Lachy Gillespie. “Congratulations Caterina on your beautiful news! Looks like there will be a couple more red Wiggles to join us all! Can’t wait to meet them!” Red Wiggle Simon Pryce said. “You’re going to bring so much love and happiness to your twin girl’s lives. Looking forward to the beautiful songs we'll sing and dance to with the newest Wiggles!” wrote Purple Wiggle John Pearce. Mete has been performing with the band since 2003 but officially became a Red Wiggle in 2021. Tour dates for the Wiggles in Australia are currently scheduled for March, April and July and Mete will continue performing with the group until her maternity leave begins later in the year. Images: Instagram

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