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Outrage after shirtless man knocks out 92-year-old woman

<p>In a horrifying broad daylight attack that has shaken the Williamstown community southwest of Melbourne, CCTV footage has captured the moment a shirtless man allegedly knocked a 92-year-old woman unconscious outside a busy shopping centre.</p> <p>The unprovoked incident occurred just after midday, as the elderly woman was walking along Douglas Parade in Williamstown. According to Victoria Police, a shirtless man approached her and suddenly swung his arm, striking her in the head. The blow sent the woman crashing to the pavement, rendering her unconscious.</p> <p>Disturbing CCTV vision shows the man calmly walking away from the scene as the elderly victim lies motionless on the ground. Witnesses can be seen rushing to her aid moments later, with some members of the public reportedly restraining the man until police arrived.</p> <p>Ambulance Victoria confirmed the woman was transported to hospital in a stable condition. Miraculously, her injuries are not considered life-threatening.</p> <p>In a statement later released from her hospital bed, the woman expressed deep gratitude to those who came to her aid.</p> <p>"I wish to thank all those who have been so caring of me," she said. "I remember nothing of the actual incident, but when I woke up, I was surrounded by the police and ambulance and caring onlookers. I wish to thank everyone for their concern. I'm pleased to go home as I have a loving family and supportive friends."</p> <p>The alleged attacker, a 39-year-old man with no fixed address, was arrested on the scene and has since been charged with intentionally causing injury.</p> <p>Police are continuing their investigation and are urging anyone who witnessed the attack or has further footage to come forward.</p> <p><em>Images: Victoria Police</em></p>

Caring

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"Find a life worth enjoying": King Charles opens up on his battle with cancer

<p>King Charles III has opened up publicly for the first time about his battle with cancer, offering a heartfelt reflection on the lessons he has learned during a special event at Buckingham Palace.</p> <p>The monarch, who was diagnosed with cancer in February 2024, described the experience as one that “brings into sharp focus the very best of humanity”, as he addressed guests gathered to celebrate community initiatives raising cancer awareness and supporting those affected by the disease.</p> <p>“Each diagnosis, each new case, will be a daunting and at times frightening experience for those individuals and their loved ones,” the King said. “It has certainly given me an even deeper appreciation of the extraordinary work undertaken by the remarkable organisations and individuals gathered here this evening.”</p> <p>The event was attended by healthcare professionals, volunteers, advocates and families affected by cancer, many of whom Charles has supported throughout his public life. He praised their efforts, noting that his own experience had reinforced a long-held belief: that compassion and connection are vital to the healing journey.</p> <p>“The darkest moments of illness can be illuminated by the greatest compassion,” he said, highlighting the roles of hospice volunteers, specialist nurses and support groups in forming what he called a “community of care”.</p> <p>Charles also expressed his family's deep gratitude to the healthcare professionals involved in cancer treatment across the UK. “They have my whole family’s deepest admiration and gratitude,” he said. “Their care represents the very best our country can offer.”</p> <p>While the King has kept the specific details of his condition private, Buckingham Palace confirmed he was <a href="https://www.oversixty.com.au/health/caring/king-charles-admitted-to-hospital" target="_blank" rel="noopener">hospitalised last month</a> due to side effects from his treatment. His diagnosis came just weeks before Princess Kate, 43, revealed she was undergoing preventative chemotherapy, sparking concern and sympathy across the nation and beyond.</p> <p>Global statistics underscore the urgency of the fight against cancer: in 2022, approximately 20 million new cases were diagnosed worldwide, with 9.7 million lives lost, according to the American Cancer Society.</p> <p>Concluding his remarks, King Charles shared a quote from Dame Deborah James – the beloved British journalist and campaigner who died of bowel cancer in 2022 – whose parents were in attendance at the Palace.</p> <p>“‘Find a life worth enjoying; take risks; love deeply; have no regrets; and always, always have rebellious hope,’” he said.</p> <p><em>Image: Sunrise</em></p>

Caring

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Andre Agassi victorious in pro pickleball debut!

<p>Andre Agassi, former tennis demigod and proud wearer of 1990s denim shorts, just served up a win in his professional pickleball debut, the sport that sounds like a snack and plays like a caffeine-fuelled family reunion in Florida.</p> <p>Fresh off turning 55 (and presumably fuelled by birthday cake and a lifetime supply of Voltarin), Agassi teamed up with 18-year-old phenom Anna Leigh Waters. Together, they defeated a duo of teens young enough to still ask permission before downloading apps. The final score: 11-8, 9-11, 11-7 – a tight match that was equal parts strategy, reflex and Agassi’s uncanny ability to intimidate opponents with his résumé.</p> <p>Let’s take a moment to appreciate this image: one of tennis’s all-time greats, who once faced Pete Sampras at Wimbledon, now facing… someone who probably wasn't alive when Agassi last hoisted a Grand Slam trophy. And yet, here he is, paddle in hand, knees holding together like true American heroes, navigating a sport that’s basically what would happen if tennis and ping pong had a baby in a Florida retirement community.</p> <p>Agassi, who retired from tennis in 2006 and was inducted into the Hall of Fame when flip phones still roamed the earth, has since dabbled in pickleball exhibition matches, mostly as an excuse to promote paddle gear online and to remind the world that he still has better footwork than most 25-year-olds.</p> <blockquote class="twitter-tweet"> <p dir="ltr" lang="en">✅ make pro Pickleball debut<br />✅ WIN pro Pickleball debut</p> <p>Andre Agassi and Anna Leigh Waters take home the W! <a href="https://t.co/ONUqDLaxWc">pic.twitter.com/ONUqDLaxWc</a></p> <p>— CBS Sports Network (@CBSSportsNet) <a href="https://twitter.com/CBSSportsNet/status/1917629532716073248?ref_src=twsrc%5Etfw">April 30, 2025</a></p></blockquote> <p>Pickleball, in case you’ve been trapped under a yoga mat, is the fastest-growing sport in America, and is making huge strides here in Australia too. It’s played with paddles, a plastic wiffleball, and the unwavering confidence of people who own ergonomic lawn chairs. It now boasts over 13 million U.S. players and rising – about 12.9 million of whom are currently trying to explain the rules to their confused spouses.</p> <p>Naturally, Agassi wasn’t quite sure how to feel about entering the pro scene.</p> <p>"I have this conflict, like I can't tell. Is this fun? Is this anxiety?" he admitted, possibly while trying to remember if his insurance covers pickleball-related injuries. He also joked that many of his tennis peers were tuning in “to watch a slow-motion train wreck”. (Spoiler: it never crashed.)</p> <p>His personal goal for the tournament wasn’t medals or glory – it was approval from his teenaged partner. “A win for me will be when this is over and Anna Leigh looks at me and says, ‘Do you want to play again?’” he said. </p> <p>While it’s too early to say whether this marks the start of a new career or just an elaborate midlife crisis with a paddle, one thing’s for sure: pickleball will never be the same.</p> <p>And who knows? At this rate, Roger Federer could be lacing up orthopaedic sneakers any minute now...</p> <p><em>Images: Instagram</em></p>

Body

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Forming new habits can take longer than you think. Here are 8 tips to help you stick with them

<div class="theconversation-article-body"> <p>If you’ve ever tried to build a new habit – whether that’s exercising more, eating healthier, or going to bed earlier – you may have heard the popular claim that it only takes 21 days to form a habit.</p> <p>It’s a neat idea. Short, encouraging and full of promise. But there’s just one problem: it’s not true.</p> <p>The 21-day myth can be traced back to <a href="https://www.amazon.com/gp/product/0671700758/ref=as_li_qf_sp_asin_il_tl?ie=UTF8&amp;camp=1789&amp;creative=9325&amp;creativeASIN=0671700758&amp;linkCode=as2&amp;tag=jamesclear-20&amp;linkId=6DQ32IRAG3LU4PKA">Maxwell Maltz</a>, a plastic surgeon in the 1960s, who observed it took about three weeks for his patients to adjust to physical changes. This idea was later picked up and repeated in self-help books, eventually becoming accepted wisdom.</p> <p>But as psychologists and behavioural scientists have since discovered, habit formation is <a href="https://www.scientificamerican.com/article/how-long-does-it-really-take-to-form-a-habit/">much more complex</a>.</p> <h2>How long does it really take?</h2> <p>A <a href="https://onlinelibrary.wiley.com/doi/10.1002/ejsp.674">2010 study</a> followed volunteers trying to build simple routines – such as drinking water after breakfast or eating a daily piece of fruit – and found it took a median of 66 days for the behaviour to become automatic.</p> <p>We recently <a href="https://www.mdpi.com/2227-9032/12/23/2488">reviewed several studies</a> looking at how long it took people to form health-related habits. We found, on average, it took around two to five months.</p> <p>Specifically, the studies that measured time to reach automaticity (when a behaviour becomes second nature) found that habit formation took between 59 and 154 days. Some people developed a habit in as few as four days. Others took nearly a year.</p> <p>This wide range highlights that habit formation isn’t one-size-fits-all. It depends on what the behaviour is, how often it’s repeated, how complex it is, and who’s doing it.</p> <h2>What determines whether a habit will stick?</h2> <p>Habit strength plays a key role in consistency. A <a href="https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2021.626750/full">2021 systematic review</a> focused on physical activity and found the stronger the habit (meaning the more automatic and less effortful the behaviour felt) the more likely people were to exercise regularly.</p> <p>It’s not entirely surprising that easy, <a href="https://bjgp.org/content/62/605/664">low-effort behaviours</a> such as drinking water or taking a daily vitamin tend to form faster than complex ones like training for a marathon.</p> <p>But whatever the habit, <a href="https://www.nature.com/articles/s44159-024-00305-0">research shows</a> sticking to it is not just about boosting motivation or willpower. Interventions that actively support habit formation – through repetition, cues and structure – are much more effective for creating lasting change.</p> <p>For example, programs that encourage people to schedule regular exercise at the same time each day, or apps that send reminders to drink water after every meal, help build habits by making the behaviour easier to repeat and harder to forget.</p> <p>Our <a href="https://www.mdpi.com/2227-9032/12/23/2488">research</a>, which drew on data from more than 2,600 people, showed habit-building interventions can make a real difference across a range of behaviours – from flossing and healthy eating to regular exercise.</p> <p>But what stood out most was that even small, everyday actions can grow into powerful routines, when repeated consistently. It’s not about overhauling your life overnight, but about steadily reinforcing behaviours until they become second nature.</p> <h2>8 tips for building lasting habits</h2> <p>If you’re looking to build a new habit, here are some science-backed tips to help them stick:</p> <ol> <li> <p>Give it time. Aim for consistency over <a href="https://www.mdpi.com/2227-9032/12/23/2488">60 days</a>. It’s not about perfection – missing a day won’t reset the clock.</p> </li> <li> <p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3505409/">Make it easy</a>. Start small. Choose a behaviour you can realistically repeat daily.</p> </li> <li> <p>Attach your new habit <a href="https://www.mdpi.com/2227-9032/12/23/2488">to an existing routine</a>. That is, make the new habit easier to remember by linking it to something you already do – such as flossing right before you brush your teeth.</p> </li> <li> <p><a href="https://www.tandfonline.com/doi/full/10.1080/0144929X.2020.1801840">Track your progress</a>. Use a calendar or app to tick off each successful day.</p> </li> <li> <p>Build in <a href="https://www.sciencedirect.com/science/article/pii/S2212267215011181?casa_token=-VKsr03fXOUAAAAA:pKV0oAB5VVuj8RcPAW5T7prjo3efSVpi6P6TXFoeTLHBX_vFK0ttF6tFM9-8Fp6o45XPu_lcij5d">rewards</a>, for example making a special coffee after a morning walk or watching an episode of your favourite show after a week of consistent workouts. Positive emotions help habits stick, so celebrate small wins.</p> </li> <li> <p>Morning is best. Habits practised <a href="https://psycnet.apa.org/doiLanding?doi=10.1037%2Fhea0000510">in the morning</a> tend to form more reliably than those attempted at night. This may be because people typically have more motivation and fewer distractions earlier in the day, making it easier to stick to new routines before daily demands build up.</p> </li> <li> <p>Personal choice boosts success. People are more likely to stick with habits <a href="https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2020.00560/full">they choose themselves</a>.</p> </li> <li> <p><a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/ejsp.674">Repetition</a> in a stable context is key. Performing the same behaviour in the same situation (such as walking right after lunch each day) increases the chances it will become automatic.</p> </li> </ol> <h2>Why the 21-day myth matters</h2> <p>Believing habits form in 21 days sets many people up to fail. When change doesn’t “click” within three weeks, it’s easy to feel like you’re doing something wrong. This can lead to frustration, guilt and giving up entirely.</p> <p>By contrast, understanding the real timeline can help you stay motivated when things feel slow.</p> <p>Evidence shows habit formation usually takes at least two months, and sometimes longer. But it also shows change is possible.</p> <p>Our <a href="https://www.mdpi.com/2227-9032/12/23/2488">research</a> and <a href="https://bjgp.org/content/62/605/664">other evidence</a> confirm that repeated, intentional actions in stable contexts really do become automatic. Over time, new behaviours can feel effortless and deeply ingrained.</p> <p>So whether you’re trying to move more, eat better, or improve your sleep, the key isn’t speed – it’s consistency. Stick with it. With time, the habit will stick with you.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/255118/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em>By</em> <em><a href="https://theconversation.com/profiles/ben-singh-1297213">Ben Singh</a>, Research Fellow, Allied Health &amp; Human Performance, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> and <a href="https://theconversation.com/profiles/ashleigh-e-smith-201327">Ashleigh E. Smith</a>, Associate Professor, Healthy Ageing, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/forming-new-habits-can-take-longer-than-you-think-here-are-8-tips-to-help-you-stick-with-them-255118">original article</a>.</em></p> <p><em>Image: Shuttertock</em></p> </div>

Mind

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Brain disorder more common than MS – but often goes undiagnosed

<div class="theconversation-article-body"> <p>Imagine suddenly losing the ability to move a limb, walk or speak. You would probably recognise this as a medical emergency and get to hospital.</p> <p>Now imagine the doctors at the hospital run some tests and then say, “Good news! All your tests were normal, clear scans, and nothing is wrong. You can go home!” Yet, you are still experiencing very real and disabling symptoms.</p> <p>Unfortunately, <a href="https://doi.org/10.1080/09638288.2024.2333491">this is the experience of many people</a> with functional neurological disorder. Even worse, some are blamed and reprimanded for <a href="https://academic.oup.com/brain/article/148/1/27/7750481?login=false">exaggerating</a> or faking their symptoms.</p> <p>So, what is this disorder, and why is it so challenging to recognise and treat?</p> <h2>What is functional neurological disorder?</h2> <p><a href="https://my.clevelandclinic.org/health/diseases/neurological-disorders">Neurological disorders</a> are conditions that affect how the nervous system works. The nervous system sends and receives messages between the brain and other parts of your body to regulate a wide range of functions, such as movement, speaking, vision, thinking and digestion.</p> <p>To the untrained eye, functional neurological disorder can resemble other conditions such as stroke, multiple sclerosis or epilepsy.</p> <p>But, unlike these conditions, functional neurological symptoms <a href="https://neurosymptoms.org/en/causes/how-was-it-happened/">aren’t due</a> to damage or a disease process affecting the nervous system. This means the disorder doesn’t appear on routine brain imaging and other tests.</p> <p>Functional symptoms are, instead, due to dysfunction in the processing of information between several brain networks. Simply put, <a href="https://neurosymptoms.org/en/causes/how-was-it-happened/">it’s a problem</a> of the brain’s software, not the hardware.</p> <h2>What are the symptoms?</h2> <p>Functional neurological disorder can produce a kaleidoscope of diverse and changing symptoms. This often adds to confusion for patients and make diagnosis more challenging.</p> <p><a href="https://neurosymptoms.org/en/symptoms/">Symptoms</a> may include paralysis or abnormal movements such as tremors, jerks and tics. This often leads to difficulty walking or coordinating movements.</p> <p>Sensory symptoms may involve numbness, tingling or loss of vision.</p> <p>Dissociative symptoms, such as functional seizures and blackouts, are also common.</p> <p>Some people experience cognitive symptoms including brain fog or problems finding the right words. Fatigue and chronic pain frequently coexist with these symptoms.</p> <p>These symptoms can be severe and distressing and, without treatment, <a href="https://pubmed.ncbi.nlm.nih.gov/31167232/">can persist for years</a>. For example, some people with functional neurological disorder cannot walk and must use a wheelchair for decades.</p> <p>Diagnosis involves <a href="https://www.bmj.com/content/371/bmj.m3745">identifying established diagnostic signs</a> and ensuring no other diagnoses are missed. This process is best carried out by an experienced neurologist or neuropsychiatrist.</p> <h2>How common is it?</h2> <p>Functional neurological disorder is one of the most common medical conditions seen in <a href="https://doi.org/10.1001/jamaneurol.2020.3753">emergency care</a> and in <a href="https://doi.org/10.1093/brain/awp220">outpatient neurology clinics</a>.</p> <p>It affects around <a href="https://doi.org/10.1136/jnnp-2024-334767">10–22 people per 100,000 per year</a>. This makes it more common than multiple sclerosis.</p> <p>Despite this, it is often under-recognised and misunderstood by health-care professionals. This leads to <a href="https://academic.oup.com/brain/article/148/1/27/7750481?login=false">delays in diagnosis and treatment</a>.</p> <p>This lack of awareness also contributes to the perception that it’s rare, when it’s actually common among neurological disorders.</p> <h2>Who does functional neurological disorder affect?</h2> <p>This condition can affect anyone, although it is more common in women and younger people. Around two thirds of patients are female, but this <a href="https://jnnp.bmj.com/content/93/6/609">gender disparity reduces with age</a>.</p> <p>Understanding of the disorder has <a href="https://pubmed.ncbi.nlm.nih.gov/33722822/">developed significantly over the past few decades</a>, but there’s still more to learn. Several biological, psychological, and social factors can <a href="https://pubmed.ncbi.nlm.nih.gov/35430029/">predispose people</a>.</p> <p>Genetics, traumatic life experiences, anxiety and depression can increase the risk. Stressful life events, illness, or physical injuries can trigger or worsen existing symptoms.</p> <p>But not everyone with the disorder has experienced significant trauma or stress.</p> <h2>How is it treated?</h2> <p>If left untreated, about <a href="https://doi.org/10.1093/brain/awz138">half the people</a> with this condition will remain the same or their symptoms will worsen. However, with the help of experienced clinicians, many people can make rapid recoveries when treatment starts early.</p> <p>There are no specific medications for functional neurological disorder but personalised rehabilitation guided by experienced clinicians is <a href="https://fndhope.org/living-fnd/">recommended</a>.</p> <p>Some people may need a team of multidisciplinary clinicians that may include physiotherapists, occupational therapists, speech therapists, psychologists and doctors.</p> <p>People also need accurate information about their condition, because <a href="https://doi.org/10.1093/brain/aws129">understanding and beliefs</a> about the disorder play an important role in recovery. Accurate information helps patients to develop more realistic expectations, reduces anxiety and can empower people to be more active in their recovery.</p> <p>Treating common co-existing conditions, such as anxiety or depression, can also <a href="https://www.bmj.com/content/376/bmj.o64.abstract">be helpful</a>.</p> <h2>A dark history</h2> <p>The origins of the disorder are deeply rooted in the sexist <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8564048/">history of its pre-scientific ancestor – hysteria</a>. The legacy of hysteria has cast a long shadow, contributing to a misogynistic bias in perception and treatment. This historical context has led to ongoing stigma, where symptoms were often labelled as psychological and not warranting treatment.</p> <p>Women with functional symptoms often face scepticism and dismissal. In some cases, <a href="https://jnnp.bmj.com/content/94/10/855">significant harm</a> occurs through stigmatisation, inadequate care and poor management. Modern medicine has attempted to address these biases by recognising functional neurological disorder as a legitimate condition.</p> <p>A <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11414792/">lack of education</a> for medical professionals likely contributes to stigma. Many <a href="https://doi.org/10.1016/j.jocn.2019.06.008">clinicians report low confidence and knowledge</a> about their ability to manage the disorder.</p> <h2>A bright future?</h2> <p>Fortunately, awareness, research and interest has grown over the past decade. Many treatment approaches are being trialled, including <a href="https://www.physio4fmd.org/">specialist physiotherapy</a>, <a href="https://jnnp.bmj.com/content/92/1/36.abstract">psychological therapies</a> and <a href="https://pubmed.ncbi.nlm.nih.gov/35115389/">non-invasive brain stimulation</a>.</p> <p>Patient-led organisations and <a href="https://fndhope.org/">support networks</a> are making headway advocating for improvements in health systems, research and education. The goal is to unite patients, their families, clinicians, and researchers to advance a new standard of care across the world.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/250501/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em>By</em> <a href="https://theconversation.com/profiles/benjamin-scrivener-2329913"><em>Benjamin Scrivener</em></a><em>, PhD Candidate, Faculty of Medical and Health Sciences, <a href="https://theconversation.com/institutions/university-of-auckland-waipapa-taumata-rau-1305">University of Auckland, Waipapa Taumata Rau</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/tremors-seizures-and-paralysis-this-brain-disorder-is-more-common-than-multiple-sclerosis-but-often-goes-undiagnosed-250501">original article</a>.</em></p> <p><em>Image: Shutterstock</em></p> </div>

Body

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Pope Francis' cause of death and burial wishes revealed

<p>The Vatican has confirmed that Pope Francis died from a stroke followed by heart failure, according to an official statement released by the Vatican press office. The 88-year-old pontiff passed away on Easter Monday, April 21, with underlying health conditions also contributing to his death.</p> <p>In a statement signed by Andrea Arcangeli, Director of the Health and Hygiene Directorate of the Vatican City State, the Vatican revealed that Francis had suffered a previous episode of acute respiratory failure, along with arterial hypertension and type II diabetes.</p> <p>Pope Francis made his final public appearance on Easter Sunday, where he delivered a brief Easter blessing to thousands gathered in St Peter’s Square. Unable to finish reading his address, the ailing pope sat as an aide delivered the rest of the speech, which called for peace in war-torn regions such as Gaza, Ukraine and Sudan.</p> <p>Following his death, the Vatican also made public the burial wishes outlined in the pope’s will. Francis requested a simple burial in the ground at Rome’s Basilica di Santa Maria Maggiore – marked only with the Latin inscription <em>Franciscus</em>. This will be the first time in over a century that a pope will be buried outside the Vatican.</p> <p>According to the will, an anonymous benefactor has agreed to cover the costs of his burial.</p> <p>With the pontiff’s passing, the Catholic Church now enters a traditional period of mourning known as the Novendiales, lasting nine days. During this time, Pope Francis will lie in state as preparations for his funeral are made.</p> <p>The conclave – the sacred process to elect a new pope – is expected to begin no sooner than 15 days and no later than 20 days following his death.</p> <p>Pope Francis, born Jorge Mario Bergoglio, became the first pope from the Americas and the first Jesuit pope. His death marks the end of a papacy defined by humility, progressive stances and a deep focus on global humanitarian issues.</p> <p><em>Images: Wikimedia Commons</em></p>

Caring

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A simple, science-backed way to sharpen thinking and improve memory – and it's not what you think

<div class="theconversation-article-body">Many of us turn to Sudoku, Wordle or brain-training apps to sharpen our minds. But research is increasingly showing one of the best ways to boost memory, focus and brain health is exercise.</p> <p>Our <a href="https://bjsm.bmj.com/content/early/2025/03/06/bjsports-2024-108589">new research</a> reviewed data from more than 250,000 participants across 2,700 studies. We found exercise helps boost brain function – whether it’s walking, cycling, yoga, dancing, or even playing active video games such as Pokémon GO.</p> <p>Moving your body improves how we think, make decisions, remember things and stay focused – no matter your age.</p> <h2>What the science says</h2> <p>Our review adds to a growing body of research that shows regular physical activity <a href="https://bjsm.bmj.com/content/early/2025/03/06/bjsports-2024-108589">improves</a> three key areas of brain function:</p> <ul> <li> <p>cognition, which is your overall ability to think clearly, learn and make decisions</p> </li> <li> <p>memory, especially short-term memory and the ability to remember personal experiences</p> </li> <li> <p>executive function, which includes focus, planning, problem-solving and managing emotions.</p> </li> </ul> <p>We conducted an umbrella review, which means we looked at the results of more than 130 high-quality research reviews that had already combined findings from many exercise studies. These studies usually involved people starting a new, structured exercise program, not just tracking the exercise they were already doing.</p> <p>To assess the effects on cognition, memory and executive function, the original studies used a range of brain function tests. These included things like remembering word lists, solving puzzles, or quickly switching between tasks – simple activities designed to reliably measure how well the brain is working.</p> <p>The improvements were small to moderate. On average, exercise led to a noticeable boost in cognition, with slightly smaller but still meaningful gains in memory and executive function.</p> <p>The benefits showed up across all age groups, though children and teens saw major gains in memory.</p> <p>People with attention-deficit hyperactivity disorder (ADHD) showed greater improvements in executive function after physical activity than other population groups.</p> <p>The brain started responding fairly quickly – many people experienced improvements after just 12 weeks of starting regular exercise.</p> <p>Generally, the greatest benefits were seen in those doing at least 30 minutes of exercise on most days of the week, aiming for a total of about 150 minutes per week.</p> <h2>What’s happening in the brain?</h2> <p>Activities such as walking or cycling can <a href="https://www.pnas.org/doi/abs/10.1073/pnas.1015950108">increase the size of the hippocampus</a>, the part of the brain responsible for memory and learning.</p> <p>In <a href="https://www.pnas.org/doi/full/10.1073/pnas.1015950108">one study</a>, older adults who did aerobic exercise for a year grew their hippocampus by 2%, effectively reversing one to two years of age-related brain shrinkage.</p> <p>More intense workouts, such as running or high-intensity interval training, can further <a href="https://onlinelibrary.wiley.com/doi/full/10.1155/2017/8305287">boost neuroplasticity</a> – the brain’s ability to adapt and rewire itself. This helps you learn more quickly, think more clearly and stay mentally sharp with age.</p> <h2>Another reason to get moving</h2> <p>The world’s population is ageing. By 2030, <a href="https://www.who.int/news-room/fact-sheets/detail/ageing-and-health">one in six of people will be aged over 60</a>. With that comes a rising risk of dementia, Alzheimer’s disease and cognitive decline.</p> <p>At the same time, many adults aren’t moving enough. One in three adults <a href="https://www.who.int/news-room/fact-sheets/detail/physical-activity">aren’t meeting the recommended levels</a> of physical activity.</p> <p>Adults <a href="https://www.who.int/initiatives/behealthy/physical-activity">should aim for</a> at least 150 of moderate exercise – such as brisk walking – each week, or at least 75 minutes of more vigorous activity, like running.</p> <p>It’s also important to incorporate muscle-strengthening exercises, such as lifting weights, into workouts at least twice a week.</p> <h2>Everyday movement counts</h2> <p>You don’t need to run marathons or lift heavy weights to benefit. Our study showed lower-intensity activities such as yoga, tai chi and “exergames” (active video games) can be just as effective – sometimes even more so.</p> <p>These activities engage both the brain and body. Tai chi, for instance, requires focus, coordination and memorising sequences.</p> <p>Exergames often include real-time decision-making and rapid response to cues. This trains attention and memory.</p> <p>Importantly, these forms of movement are inclusive. They can be done at home, outdoors, or with friends, making them a great option for people of all fitness levels or those with limited mobility.</p> <p>Although you may already be doing a lot through daily life – like walking instead of driving or carrying shopping bags home – it’s still important to find time for structured exercise, such as lifting weights at the gym or doing a regular yoga class, to get the full benefits for your brain and body.</p> <h2>Real-life applications</h2> <p>If you’re a grandparent, consider playing Wii Sports virtual tennis or bowling with your grandchild. If you’re a teenager with signs of ADHD, try a dance class, and see if it impacts your concentration in class. If you’re a busy parent, you might be more clear-headed if you can squeeze a 20-minute yoga video session between meetings.</p> <p>In each of these cases, you’re not just being active, you’re giving your brain a valuable tune-up. And unlike most brain-training apps or supplements, exercise delivers far reaching benefits, including improved <a href="https://www.sciencedirect.com/science/article/pii/S1389945721002914?casa_token=pXaOJcQJ7d0AAAAA:0i4BjaxqJ21AQ2bGXI4DfQ6twKNybrg7c2f0_Xs7t-hWyDOH0SuKGTfruy-JlC_rMokUM3iWdlSQ">sleep</a> and <a href="https://bjsm.bmj.com/content/57/18/1203">mental health</a>.</p> <p>Workplaces and schools are starting to take note. <a href="https://onlinelibrary.wiley.com/doi/10.1002/smi.2654">Short movement breaks</a> are being introduced during the workday to improve employee focus.</p> <p>Schools that incorporate <a href="https://ijbnpa.biomedcentral.com/articles/10.1186/s12966-017-0569-9">physical activity</a> into the classroom are seeing improvements in students’ attention and academic performance.</p> <p>Exercise is one of the most powerful and accessible tools we have for supporting brain health. Best of all, it’s free, widely available and it’s never too late to start.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/253751/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em>By <a href="https://theconversation.com/profiles/ben-singh-1297213">Ben Singh</a>, Research Fellow, Allied Health &amp; Human Performance, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a> and <a href="https://theconversation.com/profiles/ashleigh-e-smith-201327">Ashleigh E. Smith</a>, Associate Professor, Healthy Ageing, <a href="https://theconversation.com/institutions/university-of-south-australia-1180">University of South Australia</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/heres-a-simple-science-backed-way-to-sharpen-your-thinking-and-improve-your-memory-253751">original article</a>.</em></p> <p><em>Image: Shutterstock</em></p> </div>

Mind

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"Absolutely stunning!": Jelena Dokic wows fans with new look

<p>Former tennis star Jelena Dokic has debuted a striking new look, showcasing her dramatic weight loss and inspiring thousands with her message of self-love.</p> <p>The 41-year-old, once ranked world No. 4, made a radiant return to the spotlight as part of Channel 9’s coverage of the Billie Jean King Cup. A photo from the broadcast set quickly sparked an outpouring of support from fans, celebrating not just her transformation, but her ongoing role as a symbol of strength and positivity.</p> <p>“Back in the studio and back doing the tennis and TV with my @channel9 @wwos family,” Dokic shared with her 285,000 Instagram followers on Thursday. “Nice little lead into the next 3 grand slams of the year with a @billiejeankingcup week.”</p> <p>Supportive messages flooded the post, with fans praising her radiant presence. “You’re a dead set LEGEND Jelena,” one admirer wrote, while another added, “Absolutely stunning!”</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/p/DIQMMW5pIcp/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/DIQMMW5pIcp/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by JELENA DOKIC 🇦🇺🇦🇺🇦🇺 (@dokic_jelena)</a></p> </div> </blockquote> <p>Dokic has been open about her personal struggles, candidly discussing her battles with mental health, weight challenges and online bullying. In a heartfelt Instagram post from March 11, she reflected on her journey, using side-by-side images to convey a powerful message about body image.</p> <p>“What is the difference between the two images?” she asked. “Nothing except what you see on the outside, my BODY SIZE. I am the same hardworking person, respectful, generous, empathetic, compassionate, humble, kind, driven, strong, resilient, capable and loving person, woman and friend.”</p> <p>She continued, urging her followers to look beyond appearances: “Beauty has nothing to do with looks. It’s how you are as a person. It’s how you make others feel especially about themselves. No beauty shines brighter than that of a kind heart.”</p> <p>Now thriving as an author, expert tennis commentator and vocal advocate for mental health and body positivity, Dokic continues to inspire others with her authenticity and courage. Her documentary <em>Unbreakable</em>, which aired on Channel 9 earlier this year after its successful cinematic release in December 2024, has been met with rave reviews for its raw and honest portrayal of her life and career.</p> <p><em>Image: Instagram</em></p>

Body

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Hollywood legend reveals secret cancer battle

<p>Hollywood icon Anjelica Huston has opened up for the first time about her private battle with cancer, revealing she was diagnosed back in 2019 but is now celebrating four years of being cancer-free.</p> <p>The Oscar-winning actress, 73, shared that the diagnosis came as a “big shock” shortly after the release of <em>John Wick: Chapter 3 – Parabellum</em>, in which she starred alongside Keanu Reeves and Halle Berry. While Huston chose not to disclose the exact type of cancer she faced, she expressed pride in overcoming the illness and praised her medical team for their care.</p> <p>“It came as a big shock, but it made me conscious of what I shouldn’t do, of places I shouldn’t go,” Huston told <em>People</em> magazine. “Sometimes you feel like you don't want to talk about it for the obvious reasons, but there's a lot to be said for talking about it and getting it out there and celebrating the fact that one's come through.”</p> <p>Reflecting on her journey, she added, “I managed to survive it, and I’m proud of myself.”</p> <p>Huston, best known for her roles in <em>The Addams Family</em>, <em>The Witches</em>, and <em>Prizzi's Honor</em>, comes from a legendary Hollywood lineage. She is the daughter of famed director and screenwriter John Huston and the granddaughter of Canadian star Walter Huston. Several of her siblings have also pursued acting careers.</p> <p>Her personal life has also captured public interest over the years. Huston famously dated actor Jack Nicholson, describing their relationship as an "emotional rollercoaster." In 1992, she married sculptor Robert Graham, who sadly passed away in 2008.</p> <p>Now, with her cancer battle behind her, Huston is embracing life with renewed appreciation and strength, inspiring fans worldwide.</p> <p><em>Images: Instagram</em></p>

Caring

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A new COVID variant is on the rise: what you need to know

<div class="theconversation-article-body"> <p>More than five years since COVID was <a href="https://www.who.int/europe/emergencies/situations/covid-19">declared a pandemic</a>, we’re still facing the regular emergence of new variants of the virus, SARS-CoV-2.</p> <p>The latest variant on the rise is LP.8.1. It’s <a href="https://www.health.gov.au/resources/collections/australian-respiratory-surveillance-reports-2025">increasing in Australia</a>, making up close to <a href="https://www.health.nsw.gov.au/Infectious/covid-19/Documents/respiratory-surveillance-20250322.pdf">one in five COVID cases</a> in New South Wales.</p> <p>Elsewhere it’s become even more dominant, comprising at least three in five cases <a href="https://inews.co.uk/news/health/lp-covid-variant-cases-future-waves-3598768">in the United Kingdom</a>, for example.</p> <p>So what is LP.8.1? And is it cause for concern? Let’s look at what we know so far.</p> <h2>An offshoot of Omicron</h2> <p>LP.8.1 was first <a href="https://www.who.int/publications/m/item/risk-evaluation-for-sars-cov-2-variant-under-monitoring-lp81">detected in July 2024</a>. It’s a descendant of Omicron, specifically of KP.1.1.3, which is descended from <a href="https://theconversation.com/the-emergence-of-jn-1-is-an-evolutionary-step-change-in-the-covid-pandemic-why-is-this-significant-220285">JN.1</a>, a subvariant that caused large waves of COVID infections around the world in late 2023 and early 2024.</p> <p>The <a href="https://www.who.int/activities/tracking-SARS-CoV-2-variants">World Health Organization</a> (WHO) designated LP.8.1 as a <a href="https://www.who.int/publications/m/item/risk-evaluation-for-sars-cov-2-variant-under-monitoring-lp81">variant under monitoring</a> in January. This was in response to its significant growth globally, and reflects that it has genetic changes which may allow the virus to spread more easily and pose a greater risk to human health.</p> <p>Specifically, LP.8.1 has mutations at six locations in its spike protein, the protein which allows SARS-CoV-2 to attach to our cells. One of these mutations, V445R, is thought to allow this variant to spread more easily relative to other circulating variants. V445R has been shown to increase binding to human lung cells in <a href="https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00015-5/fulltext">laboratory studies</a>.</p> <figure class="align-center "><img src="https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=468&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=468&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=468&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=588&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=588&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/658901/original/file-20250401-56-eywcgb.png?ixlib=rb-4.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=588&amp;fit=crop&amp;dpr=3 2262w" alt="A chart showing the distribution of different COVID variants in different colours." /><figcaption><span class="caption">The proportion of COVID cases caused by LP.8.1 has been rising in New South Wales.</span> <span class="attribution"><a class="source" href="https://www.health.nsw.gov.au/Infectious/covid-19/Documents/respiratory-surveillance-20250322.pdf">NSW Health</a></span></figcaption></figure> <p>Notably, the symptoms of LP.8.1 don’t appear <a href="https://www.who.int/publications/m/item/risk-evaluation-for-sars-cov-2-variant-under-monitoring-lp81">to be any more severe</a> than other circulating strains. And the WHO has evaluated the additional public health risk LP.8.1 poses at a global level to be low. What’s more, LP.8.1 remains a variant under monitoring, rather than a variant of interest or a variant of concern.</p> <p>In other words, these changes to the virus with LP.8.1 are small, and not likely to make a big difference to the trajectory of the pandemic.</p> <h2>That doesn’t mean cases won’t rise</h2> <p>COVID as a whole is still a major national and international health concern. So far this year there have been close to <a href="https://www.health.gov.au/resources/collections/australian-respiratory-surveillance-reports-2025">45,000 new cases recorded in Australia</a>, while around <a href="https://covidlive.com.au/report/daily-hospitalised/aus">260 people are currently in hospital</a> with the virus.</p> <p>Because many people are no longer testing or reporting their infections, the real number of cases is probably far higher.</p> <p>In <a href="https://www.health.gov.au/resources/collections/australian-respiratory-surveillance-reports-2025">Australia</a>, LP.8.1 has become the <a href="https://www.health.nsw.gov.au/Infectious/covid-19/Documents/respiratory-surveillance-20250322.pdf">third most dominant strain in NSW</a> (behind <a href="https://theconversation.com/xec-is-now-in-australia-heres-what-we-know-about-this-hybrid-covid-variant-239292">XEC</a> and KP.3).</p> <p>It <a href="https://www.health.nsw.gov.au/Infectious/covid-19/Documents/respiratory-surveillance-20250322.pdf">has been growing</a> over the past couple of months and this trend looks set to continue.</p> <p>This is not to say it’s not growing similarly in other states and territories, however NSW Health publishes <a href="https://www.health.nsw.gov.au/Infectious/covid-19/Pages/reports.aspx">weekly respiratory surveillance</a> with a breakdown of different COVID variants in the state.</p> <p>Sequences of LP.8.1 in the <a href="https://gisaid.org/">GISAID database</a>, used to track the prevalence of variants around the world, increased from <a href="https://www.who.int/publications/m/item/risk-evaluation-for-sars-cov-2-variant-under-monitoring-lp81">around 3%</a> at the end of 2024 to 38% of global sequences as of <a href="https://x.com/Mike_Honey_/status/1905816340331728914">mid March</a>.</p> <p>In some countries it’s climbed particularly high. In the United States LP.8.1 is responsible for <a href="https://covid.cdc.gov/covid-data-tracker/#variant-proportions">55% of cases</a>. In <a href="https://inews.co.uk/news/health/lp-covid-variant-cases-future-waves-3598768">the UK</a>, where LP.8.1 is making up at least 60% of cases, scientists fear <a href="https://inews.co.uk/news/science/new-covid-wave-cases-hospitalisations-3611459?srsltid=AfmBOor_V7pQrPMPhUYQA2KCZgRfsI_CpxTwIRiHDFJHIJhq2kbAmD42">it may be driving a new wave</a>.</p> <h2>Will COVID vaccines work against LP.8.1?</h2> <p>Current COVID vaccines, including the most recently available <a href="https://theconversation.com/new-covid-vaccines-may-be-coming-to-australia-heres-what-to-know-about-the-jn-1-shots-237652">JN.1 shots</a>, are still expected to <a href="https://www.who.int/publications/m/item/risk-evaluation-for-sars-cov-2-variant-under-monitoring-lp81">offer good protection</a> against symptomatic and severe disease with LP.8.1.</p> <p>Nonetheless, due to its designation as a variant under monitoring, WHO member countries will continue to study the behaviour <a href="https://www.who.int/publications/m/item/risk-evaluation-for-sars-cov-2-variant-under-monitoring-lp81">of the LP.8.1 variant</a>, including any potential capacity to evade our immunity.</p> <p>While there’s no cause for panic due to LP.8.1 variant at this stage, COVID can still be a severe disease for some. Continued vigilance and vaccination, particularly <a href="https://www.health.gov.au/our-work/covid-19-vaccines/getting-your-vaccination">for medically vulnerable groups</a>, is essential in minimising the impact of the disease.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/253237/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em>By <a href="https://theconversation.com/profiles/thomas-jeffries-1511629">Thomas Jeffries</a>, Senior Lecturer in Microbiology, <a href="https://theconversation.com/institutions/western-sydney-university-1092">Western Sydney University</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/a-new-covid-variant-is-on-the-rise-heres-what-to-know-about-lp-8-1-253237">original article</a>.</em></p> <p><em>Image: Shutterstock</em></p> </div>

Caring

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Incredible new pacemaker tinier than a grain of rice

<p>Engineers from Northwestern University in the US have developed a groundbreaking pacemaker so tiny that it can fit inside the tip of a syringe – is smaller than a grain of rice – and be non-invasively injected into the body. This innovation could revolutionise cardiac care by offering a minimally invasive alternative to traditional pacemakers.</p> <p>"We have developed what is, to our knowledge, the world's smallest pacemaker," said bioelectronics pioneer John A Rogers, who led the development. The small, wireless device is biocompatible and designed to be gradually broken down and absorbed by the body, reducing the need for surgical extraction.</p> <p>Rogers and his colleagues tested the effectiveness of their tiny, temporary pacemaker in human heart tissue and animal models. Measuring just 1.8mm by 3.5mm by 1mm, the device is smaller than any previously reported pacemaker. It is paired with a soft, flexible, wireless wearable device mounted on a patient’s chest, which controls the pacing. When an irregular heartbeat is detected, the wearable device emits a light pulse that penetrates through the skin, breastbone and muscles to activate the pacemaker and regulate heart rhythm.</p> <p>While designed to work for hearts of all sizes, the pacemaker is particularly well-suited for newborns with congenital heart defects. Northwestern experimental cardiologist Igor Efimov, who co-led the study, said this device could play a<span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;"> critical role in the effective treatment</span><span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;"> of infants.</span></p> <p>"Our major motivation was children," Efimov explained. "About 1 percent of children are born with congenital heart defects, regardless of whether they live in a low-resource or high-resource country. The good news is that these children only need temporary pacing after surgery. In about seven days or so, most patients’ hearts will self-repair. But those seven days are absolutely critical."</p> <p>Researchers believe this pacemaker could provide a safer alternative to traditional pacemakers for temporary pacing in patients with bradycardia, a condition characterised by a resting heart rate below 60 beats per minute. Additionally, they suggest that the technology’s versatility could extend to broader medical applications in bioelectronic medicine, such as aiding nerve and bone healing and blocking pain.</p> <p>This revolutionary development represents a significant step forward in cardiac treatment, potentially improving outcomes for both infants and adults requiring temporary heart pacing.</p> <p><em>Images: Northwestern University</em></p>

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Do stem cell injections for knee osteoarthritis actually work?

<div class="theconversation-article-body">More than 500 million people around the world <a href="https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00163-7/fulltext">live with osteoarthritis</a>. The knee is affected more often than any other joint, with symptoms (such as pain, stiffness and reduced movement) affecting work, sleep, sport and <a href="https://www.aihw.gov.au/reports/chronic-musculoskeletal-conditions/osteoarthritis">daily activities</a>.</p> <p>Knee osteoarthritis is often thought of as thinning of the protective layer of cartilage within the joint. But we now understand it affects all the structures of the joint, including the bones, muscles and nerve endings.</p> <p>While there are things that <a href="https://www.safetyandquality.gov.au/standards/clinical-care-standards/osteoarthritis-knee-clinical-care-standard/information-consumers-osteoarthritis-knee-clinical-care-standard">can be done to manage</a> the symptoms of knee osteoarthritis, there is no cure, and many people experience persistent pain. As a result, an opportunity exists for <a href="https://www.rheuma.com.au/stem-cell-therapy-good-bad-ugly/174">as yet unproven treatments</a> to enter the market, often before regulatory safeguards can be put in place.</p> <p>Stem cell injections are one such treatment. A <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013342.pub2">new review</a> my colleagues and I published this week finds that evidence of their benefits and harms remains elusive.</p> <h2>Stem cell treatments</h2> <p>Stem cells are already established as treatments for some diseases – <a href="https://www.lymphoma.org.au/lymphoma/treatments/stem-cell-transplants/autologous-stem-cell-transplant/">mostly disorders of the blood</a>, bone marrow or immune system – which has led to suggestions they could be used for a much wider array of conditions.</p> <p>Stem cells have been touted as promising treatments for osteoarthritis because they have special properties which allow them to replicate and develop into the mature healthy cells that make up our body’s organs and other tissues, including cartilage.</p> <p>Stem cell treatments for osteoarthritis generally involve <a href="https://www.aboutstemcells.org/treatments">taking a sample of tissue</a> from a site that is rich in stem cells (such as bone marrow or fat), treating it to increase the number of stem cells, then injecting it into the joint.</p> <p>The hope is that if the right type of stem cells can be introduced into an osteoarthritic joint in the right way and at the right time, they may help to repair damaged structures in the joint, or have other effects such as reducing inflammation.</p> <p>But no matter how convincing the theory, we need good evidence for effectiveness and safety before a new therapy is adopted into practice.</p> <p>Stem cell injections have not been approved by Australia’s <a href="https://www.tga.gov.au/news/news/stem-cell-treatments-and-regulation-quick-guide-consumers#:%7E:text=Does%20the%20TGA%20regulate%20stem,does%20not%20regulate%20medical%20practice">Therapeutic Goods Administration</a> for the treatment of osteoarthritis. Nonetheless, some clinics in Australia and around the world still offer them.</p> <p>Because of the regulatory restrictions, we don’t have reliable numbers on how many procedures are being done.</p> <p>They’re not covered by Medicare, so the procedure can cost the consumer thousands of dollars.</p> <p>And, as with any invasive procedure, both the <a href="https://coroners.nsw.gov.au/documents/findings/2016/Findings%20Drysdale.pdf">harvest of stem cells</a> and the joint injection procedure may carry the potential for harm, such as infection.</p> <h2>What we found</h2> <p>Our <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013342.pub2">new review</a>, published by the independent, international group the Cochrane Collaboration, looks at all 25 randomised trials of stem cell injections for knee osteoarthritis that have been conducted worldwide to date. Collectively, these studies involved 1,341 participants.</p> <p>We found stem cell injections may slightly improve pain and function compared with a placebo injection, but the size of the improvement may be too small for the patient to notice.</p> <p>The evidence isn’t strong enough to determine whether there is any improvement in quality of life following a stem cell injection, whether cartilage regrows, or to estimate the risk of harm.</p> <p>This means we can’t confidently say yet whether any improvement that might follow a stem cell injection is worth the risk (or the cost).</p> <h2>Hope or hype?</h2> <p>It’s not surprising we invest hope in finding a transformative treatment for such a common and disabling condition. Belief in the benefits of stem cells is widespread – more than <a href="https://www.arthroscopyjournal.org/article/S0749-8063(21)00571-5/abstract">three-quarters of Americans</a> believe stem cells can relieve arthritis pain and more than half believe this treatment to be curative.</p> <p>But what happens if a new treatment is introduced to practice before it has been clearly proven to be safe and effective?</p> <p>The use of an unproven, invasive therapy is not just associated with the risks of the intervention itself. Even if the treatment were harmless, there is the risk of unnecessary cost, inconvenience, and a missed opportunity for the patient to use existing therapies that are known to be effective.</p> <p>What’s more, if we need to play catch-up to try to establish an evidence base for a treatment that’s already in practice, we risk diverting scarce research resources towards a therapy that may not prove to be effective, simply because the genie is out of the bottle.</p> <h2>Working towards a clearer answer</h2> <p>Several more large <a href="https://anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12620000870954">clinical trials</a> are currently underway, and should increase our understanding of whether stem cell injections are safe and effective for knee osteoarthritis.</p> <p>Our review incorporates “<a href="https://www.cochrane.org/news/cochranes-pioneering-role-living-evidence">living evidence</a>”. This means we will continue to add the results of new trials as soon as they’re published, so the review is always up to date, and offers a comprehensive and trustworthy summary to help people with osteoarthritis and their health-care providers to make informed decisions.</p> <p>In the meantime, there are a number of <a href="https://www.racgp.org.au/clinical-resources/clinical-guidelines/key-racgp-guidelines/view-all-racgp-guidelines/knee-and-hip-osteoarthritis/summary-plain-language">evidence-based treatment options</a>. Non-drug treatments such as physiotherapy, regular exercise, maintaining a healthy weight, and cognitive behavioural therapy can be more effective than you think. Anti-inflammatory and pain medications can also play a supporting role.</p> <p>Importantly, it’s not inevitable that osteoarthritic joints get worse with time. So, even though <a href="https://aoanjrr.sahmri.com/background">joint replacement surgery</a> is often highly effective, it’s the last resort and fortunately, many people never need to take this step.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/253404/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em>By <a href="https://theconversation.com/profiles/samuel-whittle-2357927">Samuel Whittle</a>, ANZMUSC Practitioner Fellow, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/people-are-getting-costly-stem-cell-injections-for-knee-osteoarthritis-but-we-dont-know-if-they-work-253404">original article</a>.</em></p> <p><em>Image: Shutterstock</em></p> </div>

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New study suggests shingles vaccine may lower dementia risk

<p>A groundbreaking new study suggests that getting vaccinated against shingles could offer protection against dementia, adding to the growing evidence linking viral infections to cognitive decline.</p> <p>Shingles is a painful and debilitating condition that occurs in individuals who have previously had chickenpox. The varicella-zoster virus, responsible for both diseases, can lie dormant for years before reactivating as shingles.</p> <p>The latest research, published recently in <em>Nature</em>, analysed data from over 280,000 older adults in Wales. The findings reveal that individuals who received the original live-virus shingles vaccine were 20% less likely to develop dementia than those who were not vaccinated.</p> <p>The study was made possible by a unique public health policy in Wales, which provided an unusual opportunity to compare similar populations. On September 1, 2013, the vaccine was offered to individuals who were 79 years old on that date but not to those who had turned 80. This created two nearly identical groups, differing only in their eligibility for the vaccine, allowing researchers from Germany and Stanford University to examine its impact on dementia risk.</p> <p>“This study is essentially like a randomised controlled trial, which is the gold standard in research,” said Dr Pascal Geldsetzer, a Stanford University assistant professor of medicine and senior author of the study.</p> <p>Previous research has suggested an association between the newer Shingrix vaccine – which replaced the live-virus version in 2020 – and a lower risk of dementia, particularly in women. However, earlier studies were unable to fully account for differences between vaccinated and unvaccinated individuals, such as overall health status.</p> <p>Dr Allison Aiello, a professor of epidemiology at Columbia University’s Aging Centre, praised the design of the Welsh study. “It’s like having a control group compared to a treated group,” Aiello, who was not involved in the research, said. “The 20% reduction in dementia risk is a pretty strong effect, which aligns with other findings that suggest herpes viruses might influence dementia.”</p> <p>Scientists do not yet fully understand how the varicella-zoster virus increases dementia risk. One theory is that viral reactivation may contribute to the buildup of abnormal proteins associated with Alzheimer’s disease. Another possibility is that shingles reactivation might also trigger herpes simplex virus (HSV), which has previously been linked to dementia.</p> <p>Herpes viruses, including HSV-1 and HSV-2, can linger in the body indefinitely, often reactivating when the immune system weakens with age. These viruses can infiltrate the central nervous system, potentially leading to brain inflammation and neurodegenerative effects. A 2024 study found that among 70-year-olds without dementia at the outset, those diagnosed with herpes simplex were more than twice as likely to develop dementia over 15 years.</p> <p>While the new study offers compelling evidence, it is not a definitive randomised controlled trial, cautioned Dr William Schaffner, an infectious disease expert at Vanderbilt University Medical Centre. “It’s provocative, interesting and exciting,” he said. However, he noted that it would be unethical to randomly assign people to receive or forgo the vaccine.</p> <p>The US FDA may eventually review the accumulating research and consider updating the shingles vaccine label to reflect a possible dementia-protection benefit, Schaffner added. Even if such an update does not occur, doctors may use these findings to encourage more people over 50 to get vaccinated.</p> <p>“There are still many eligible people who haven’t received the vaccine,” Schaffner said. “If they hear that it might help prevent dementia, that could be the push they need.”</p> <p><em>Image: Supplied</em></p>

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Do any non-drug treatments help back pain? Here’s what the evidence says

<div class="theconversation-article-body"> <p>Jason, a 42-year-old father of two, has been battling back pain for weeks. Scrolling through his phone, he sees ad after ad promising relief: chiropractic alignments, acupuncture, back braces, vibrating massage guns and herbal patches.</p> <p>His GP told him to “stay active”, but what does that even mean when every movement hurts? Jason wants to avoid strong painkillers and surgery, but with so many options (and opinions), it’s hard to know what works and what’s just marketing hype.</p> <p>If Jason’s experience sounds familiar, you’re not alone. Back pain is one of the most common reasons people visit a doctor. It can be challenging to manage, mainly due to widespread <a href="https://theconversation.com/having-good-posture-doesnt-prevent-back-pain-and-bad-posture-doesnt-cause-it-183732">misunderstandings</a> and the <a href="https://ebm.bmj.com/content/early/2025/03/02/bmjebm-2024-112974">overwhelming number</a> of ineffective and uncertain treatments promoted.</p> <p>We assessed the best available evidence of non-drug and non-surgical treatments to alleviate low back pain. <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014691.pub2/full">Our review</a> – published today by the independent, international group the Cochrane Collaboration – includes 31 Cochrane systematic reviews, covering 97,000 people with back pain.</p> <p>It <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014691.pub2/full">shows</a> bed rest doesn’t work for back pain. Some of the treatments that do work can depend on how long you’ve been in pain.</p> <h2>Is back pain likely to be serious?</h2> <p>There are different types of low back pain. It can:</p> <ul> <li>be short-lived, lasting less than six weeks (acute back pain)</li> <li>linger for a bit longer, for six to twelve weeks (sub-acute)</li> <li>stick around for months and even years (chronic, defined as more than 12 weeks).</li> </ul> <p>In <a href="https://www.thelancet.com/article/S0140-6736(16)30970-9/abstract">most cases</a> (90-95%), back pain is non-specific and cannot be reliably linked to a specific cause or underlying disease. This includes common structural changes seen in x-rays and MRIs of the spine.</p> <p>For this reason, imaging of the back is <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60172-0/abstract">only</a> recommended in rare situations – typically when there’s a clear suspicion of serious back issues, such as after physical trauma or when there is numbness or loss of sensation in the groin or legs.</p> <p>Many people expect to receive <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013815.pub2/full">painkillers</a> for their back pain or even surgery, but these are no longer the front-line treatment options due to limited benefits and the high risk of harm.</p> <p>International <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30489-6/fulltext">clinical guidelines</a> recommend people choose non-drug and non-surgical treatments to relieve their pain, improve function and reduce the distress commonly associated with back pain.</p> <p>So what works for different types of pain? Here’s what <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014691.pub2/full">our review found</a> when researchers compared these treatments with standard care (the typical treatment patients usually receive) or no treatment.</p> <h2>What helps for short-term back pain</h2> <p><strong>1. Stay active – don’t rest in bed</strong></p> <p>If your back pain is new, the best advice is also one of the simplest: keep moving despite the pain.</p> <p>Changing the way you move and use your body to protect it, or resting in bed, can seem like to right way to respond to pain – and may have even been recommended in the past. But we know know this excessive protective behaviour can make it harder to return to meaningful activities.</p> <p>This doesn’t mean pushing through pain or hitting the gym, but instead, trying to maintain your usual routines as much as possible. Evidence suggests that doing so won’t make your pain worse, and may improve it.</p> <p><strong>2. Multidisciplinary care, if pain lingers</strong></p> <p>For pain lasting six to 12 weeks, multidisciplinary treatment is likely to reduce pain compared to standard care.</p> <p>This involves a coordinated team of doctors, physiotherapists and psychologists working together to address the many factors contributing to your back pain persisting:</p> <ul> <li> <p>neurophysiological influences refer to how your nervous system is currently processing pain. It can make you more sensitive to signals from movements, thoughts, feelings and environment</p> </li> <li> <p>psychological factors include how your thoughts, feelings and behaviours affect your pain system and, ultimately, the experience of pain you have</p> </li> <li> <p>occupational factors include the physical demands of your job and how well you can manage them, as well as aspects like low job satisfaction, all of which can contribute to ongoing pain.</p> </li> </ul> <h2>What works for chronic back pain</h2> <p>Once pain has been around for more than 12 weeks, it can become more difficult to treat. But relief is still possible.</p> <p><strong>Exercise therapy</strong></p> <p>Exercise – especially programs tailored to your needs and preferences – is likely to reduce pain and help you move better. This could include aerobic activity, strength training or Pilates-based movements.</p> <p>It doesn’t seem to matter what type of exercise you do – it matters more that you are consistent and have the right level of supervision, especially early on.</p> <p><strong>Multidisciplinary treatment</strong></p> <p>As with short-term pain, coordinated care involving a mix of physical, occupational and psychological approaches likely works better than usual care alone.</p> <p><strong>Psychological therapies</strong></p> <p>Psychological therapies for chronic pain include approaches to help people change thinking, feelings, behaviours and reactions that might sustain persistent pain.</p> <p>These approaches are likely to reduce pain, though they may not be as effective in improving physical function.</p> <p><strong>Acupuncture</strong></p> <p>Acupuncture probably reduces pain and improves how well you can function compared to placebo or no treatment.</p> <p>While some debate remains about how it works, the evidence suggests potential benefits for some people with chronic back pain.</p> <h2>What doesn’t work or still raises uncertainty?</h2> <p>The review found that many commonly advertised treatments still have uncertain benefits or probably do not benefit people with back pain.</p> <p>Spinal manipulation, for example, has uncertain benefits in acute and chronic back pain, and it likely does not improve how well you function if you have acute back pain.</p> <p>Traction, which involves stretching the spine using weights or pulleys, probably doesn’t help with chronic back pain. Despite its popularity in some circles, there’s little evidence that it works.</p> <p>There isn’t enough reliable data to determine whether advertised treatments – such back braces, vibrating massage guns and herbal patches – are effective.</p> <h2>How can you use the findings?</h2> <p>If you have back pain, start by considering how long you’ve had it. Then explore treatment options that research supports and discuss them with your GP, psychologist or physiotherapist.</p> <p>Your health provider should reassure you about the importance of gradually increasing your activity to resume meaningful work, social and life activities. They should also support you in making informed decisions about which treatments are most appropriate for you at this stage.</p> <p><!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><em><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/253122/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" />By <a href="https://theconversation.com/profiles/rodrigo-rossi-nogueira-rizzo-1544189">Rodrigo Rossi Nogueira Rizzo</a>, Postdoctoral Research Fellow, <a href="https://theconversation.com/institutions/neuroscience-research-australia-976">Neuroscience Research Australia</a> and <a href="https://theconversation.com/profiles/aidan-cashin-2355450">Aidan Cashin</a>, NHMRC Emerging Leadership Fellow, <a href="https://theconversation.com/institutions/neuroscience-research-australia-976">Neuroscience Research Australia</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/do-any-non-drug-treatments-help-back-pain-heres-what-the-evidence-says-253122">original article</a>.</em></p> <p><em>Image: Shutterstock</em></p> </div>

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King Charles admitted to hospital

<p>Reports from Buckingham palace have revealed that King Charles has been forced to cancel a series of public engagements after being admitted to hospital due to side effects from his ongoing cancer treatment.</p> <p>The Palace released a statement on Thursday evening confirming that the 72-year-old monarch had “experienced temporary side effects that required a short period of observation in hospital” following his scheduled and ongoing medical treatment for cancer. The King has since returned to Clarence House, where he resides with Queen Camilla.</p> <p>“As a precautionary measure, acting on medical advice, tomorrow’s diary program will also be rescheduled,” the Palace added. Although the Palace did not specify the exact nature of the side effects, sources suggest such occurrences are not uncommon among cancer patients.</p> <p>A royal insider described the medical incident to <em>The Daily Mail</em> as a “most minor bump in a road that’s very much heading in the right direction”. However, in order to “protect and prioritise [his] continued very positive recovery”, King Charles has regretfully cancelled his planned engagements in Birmingham on Friday.</p> <p>The King was diagnosed with an undisclosed form of cancer in February last year and has been receiving outpatient treatment since then. Initially, he had to withdraw from public duties for several weeks but resumed engagements in April. Since then, he has travelled internationally – including a visit to Australia last October – and hosted numerous state visits while continuing his recovery.</p> <p>Last week, King Charles visited Ulster University’s Pharmacy and Pharmacology department in Northern Ireland to learn about their groundbreaking cancer research. During his visit, he shared words of encouragement with fellow cancer patients, quoting Winston Churchill’s famous phrase: “Keep buggering on.” Regarding the side effects of treatment, he remarked, “You just have to push on, don’t you?”</p> <p>While the specific type of cancer affecting the King has not been disclosed, reports suggest that it was caught at a very early stage. Royal sources remain optimistic about his recovery, and say his treatment is progressing positively.</p> <p><em>Image: Department of the Prime Minister and Cabinet/ Millie Pilkington</em></p>

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"Patrons yelled to stop": Comedy Festival rocked by death on opening night

<p>Melbourne’s comedy scene was rocked by tragedy on the opening night of this year’s International Comedy Festival, as an attendee suffered a fatal medical episode mid-show, leading to the abrupt cancellation of the event.</p> <p>The distressing incident occurred during comedian Michael Hing’s performance at the Palais Theatre, where a man on the upper level of the venue suffered a medical emergency. Attendees quickly responded, providing CPR in the dark while Hing remained unaware of the unfolding crisis.</p> <p>“[It] would have been at least 15 mins worth before the show stopping, and [it] only stopped as patrons yelled to stop performing,” one audience member told <em>The Daily Mail</em>.</p> <p>Another witness expressed dismay over the handling of the situation, stating, “I can’t believe they [the organisers] didn’t communicate with backstage to halt the show, and that it took the public to yell out to the comedian to stop for something to happen.”</p> <p>The Melbourne International Comedy Festival addressed the incident in a statement posted on Instagram, confirming the show’s cancellation.</p> <p>“Melbourne International Comedy Festival regrets to confirm that there was a medical emergency while the Opening Night Allstars Supershow was taking place this evening at the Palais Theatre,” a festival spokesman said. “The show was stopped and cancelled. The Festival will be in touch with all ticket holders tomorrow.”</p> <p>Victoria Police later confirmed the man’s death. “Police will prepare a report for the Coroner following the death of a man in St Kilda on Wednesday, 26 March,” a spokesman said. “Emergency services were called to a theatre on Lower Esplanade about 9pm. A man, who is yet to be formally identified, died at the scene.”</p> <p>Health worker Andrea Bortoli, who was sitting in the upper level’s front row, described the distressing scene as people began leaving and it “became quite obvious that someone was getting CPR. It was just obviously really distressing, so we wanted to leave,” she told <em>The Age</em>. </p> <p>Eventually, the theatre lights were turned on, and patrons were informed that the show had been cancelled.</p> <p>The Allstars Gala is one of the most anticipated nights of the festival, bringing together some of the biggest names in comedy. This year’s event was hosted by Hing.</p> <p>As news of the tragedy spread, comedian Dave Hughes expressed his sympathies on social media, writing, “All performers thoughts are with the family affected”.</p> <p><em>Images: Palais Theatre / MichaelHing.com</em></p>

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"Game changer": Aussie women welcome new early-detection cancer test

<p>Australian women will soon have access to a revolutionary blood test designed to aid in the early detection of breast cancer. The innovative test, known as BREASTEST plus™, was developed by BCAL Diagnostics and is set to complement traditional breast cancer screening methods such as mammograms and ultrasounds.</p> <p>BCAL Diagnostics chair Jayne Shaw <a href="https://7news.com.au/news/public-health/australian-first-blood-test-to-help-early-detection-of-breast-cancer-comes-to-sydney-before-nationwide-rollout-c-18153750" target="_blank" rel="noopener">revealed to 7NEWS</a> that the development of the test had taken 15 years, describing it as a "game changer" for women worldwide.</p> <p>“The breast test is a game changer for all women everywhere because it’s a blood test to detect breast cancer alongside other diagnostic tools like ultrasound and a mammogram,” Shaw said.</p> <p>She pointed out that a similar blood test for prostate cancer, which has been available since 1989, has significantly improved clinical outcomes for men. “Early diagnosis for all cancers will lead to improved survivability rates, and it was only inevitable that a blood test would be developed to diagnose breast cancer earlier,” she added.</p> <p>One of the major advantages of the new blood test is its ability to detect breast cancer in women with high breast density. Around 40-50% of Australian women undergoing screening have high breast density, which can obscure abnormalities on mammograms and make diagnosis more difficult.</p> <p>With the ability to identify breast cancer markers, the blood test will provide a valuable additional tool for detecting cancers that might otherwise go unnoticed.</p> <p>Breast Cancer Network Australia director Vicki Durston welcomed the new test, especially for its potential to improve the reporting of high breast density cases, where cancers are often missed. “Breast Cancer Network Australia has long been calling for the uplift in the breast density statement nationally to see standardised reporting across the country,” Durston said.</p> <p>She also noted that while high breast density is just one of many risk factors, the new test represents an innovative step forward in improving early detection and treatment.</p> <p>Breast cancer remains the most commonly diagnosed cancer among Australian women, accounting for approximately 28% of all new cancer cases. In 2024 alone, around 21,194 people were diagnosed with breast cancer in Australia, including 20,973 women and 221 men. However, survival rates have improved dramatically, with Australia’s peak breast cancer body reporting that the five-year survival rate has risen from 78% in 1994 to 92% in 2020, with many people living long and healthy lives beyond this period.</p> <p>While the test currently comes at an out-of-pocket cost, there is hope that the Australian government will eventually provide subsidies under Medicare to make it more accessible. The first tests will be available at the <a href="https://www.sydneybreastclinic.com.au/" target="_blank" rel="noopener">Sydney Breast Clinic</a> starting Thursday, followed by a rollout in Melbourne, with plans to expand nationwide by the end of the year.</p> <p><em>Images: Shutterstock / 7NEWS</em></p>

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How long will you live? New evidence says it’s much more about your choices than your genes

<div class="theconversation-article-body"> <p>One of the most enduring questions humans have is how long we’re going to live. With this comes the question of how much of our lifespan is shaped by our environment and choices, and how much is predetermined by our genes.</p> <p>A study recently published in the prestigious journal <a href="https://www.nature.com/articles/s41591-024-03483-9">Nature Medicine</a> has attempted for the first time to quantify the relative contributions of our environment and lifestyle versus our genetics in how we age and how long we live.</p> <p>The findings were striking, suggesting our environment and lifestyle play a much greater role than our genes in determining our longevity.</p> <h2>What the researchers did</h2> <p>This study used data from the <a href="https://www.ukbiobank.ac.uk/">UK Biobank</a>, a large database in the United Kingdom that contains in-depth health and lifestyle data from roughly 500,000 people. The data available include genetic information, medical records, imaging and information about lifestyle.</p> <p>A separate part of the study used data from a subset of more than 45,000 participants whose blood samples underwent something called “<a href="https://www.nature.com/articles/s41576-022-00511-7">proteomic profiling</a>”.</p> <p>Proteomic profiling is a relatively new technique that looks at how proteins in the body change over time to identify a person’s age at a molecular level. By using this method researchers were able to estimate how quickly an individual’s body was actually ageing. This is called their biological age, as opposed to their chronological age (or years lived).</p> <p>The researchers assessed 164 environmental exposures as well as participants’ genetic markers for disease. Environmental exposures included lifestyle choices (for example, smoking, physical activity), social factors (for example, living conditions, household income, employment status) and early life factors, such as body weight in childhood.</p> <p>They then looked for associations between genetics and environment and 22 major age-related diseases (such as coronary artery disease and type 2 diabetes), mortality and biological ageing (as determined by the proteomic profiling).</p> <p>These analyses allowed the researchers to estimate the relative contributions of environmental factors and genetics to ageing and dying prematurely.</p> <h2>What did they find?</h2> <p>When it came to disease-related mortality, as we would expect, age and sex explained a significant amount (about half) of the variation in how long people lived. The key finding, however, was environmental factors collectively accounted for around 17% of the variation in lifespan, while genetic factors contributed less than 2%.</p> <p>This finding comes down very clearly on the nurture side in the “nature versus nurture” debate. It suggests environmental factors influence health and longevity to a far greater extent than genetics.</p> <p>Not unexpectedly, the study showed a different mix of environmental and genetic influences for different diseases. Environmental factors had the greatest impact on lung, heart and liver disease, while genetics played the biggest role in determining a person’s risk of breast, ovarian and prostate cancers, and dementia.</p> <p>The environmental factors that had the most influence on earlier death and biological ageing included smoking, socioeconomic status, physical activity levels and living conditions.</p> <p>Interestingly, being taller at age ten was found to be associated with a shorter lifespan. Although this may seem surprising, and the reasons are not entirely clear, this aligns with <a href="https://www.sciencedaily.com/releases/2014/05/140509110756.htm">previous research</a> finding taller people are more likely to die earlier.</p> <p>Carrying more weight at age ten and maternal smoking (if your mother smoked in late pregnancy or when you were a newborn) were also found to shorten lifespan.</p> <p>Probably the most surprising finding in this study was a lack of association between diet and markers of biological ageing, as determined by the proteomic profiling. This flies in the face of the extensive body of evidence showing the crucial role of <a href="https://www.nature.com/articles/s43016-023-00868-w">dietary patterns</a> in chronic disease risk and longevity.</p> <p>But there are a number of plausible explanations for this. The first could be a lack of statistical power in the part of the study looking at biological ageing. That is, the number of people studied may have been too small to allow the researchers to see the true impact of diet on ageing.</p> <p>Second, the dietary data in this study, which was self-reported and only measured at one time point, is likely to have been of relatively poor quality, limiting the researchers’ ability to see associations. And third, as the relationship between diet and longevity is likely to be complex, disentangling dietary effects from other lifestyle factors may be difficult.</p> <p>So despite this finding, it’s still safe to say the food we eat is one of the most important pillars of health and longevity.</p> <h2>What other limitations do we need to consider?</h2> <p>Key exposures (such as diet) in this study were only measured at a single point in time, and not tracked over time, introducing potential errors into the results.</p> <p>Also, as this was an observational study, we can’t assume associations found represent causal relationships. For example, just because living with a partner correlated with a longer lifespan, it doesn’t mean this caused a person to live longer. There may be other factors which explain this association.</p> <p>Finally, it’s possible this study may have underestimated the role of genetics in longevity. It’s important to recognise genetics and environment don’t operate in isolation. Rather, health outcomes are shaped by their interplay, and this study may not have fully captured the complexity of these interactions.</p> <h2>The future is (largely) in your hands</h2> <p>It’s worth noting there were a number of factors such as household income, home ownership and employment status associated with diseases of ageing in this study that are not necessarily within a person’s control. This highlights the crucial role of addressing the social determinants of health to ensure everyone has the best possible chance of living a long and healthy life.</p> <p>At the same time, the results offer an empowering message that longevity is largely shaped by the choices we make. This is great news, unless you have good genes and were hoping they would do the heavy lifting.</p> <p>Ultimately, the results of this study reinforce the notion that while we may inherit certain genetic risks, how we eat, move and engage with the world seems to be more important in determining how healthy we are and how long we live.<!-- Below is The Conversation's page counter tag. 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More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/hassan-vally-202904"><em>Hassan Vally</em></a><em>, Associate Professor, Epidemiology, <a href="https://theconversation.com/institutions/deakin-university-757">Deakin University</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/how-long-will-you-live-new-evidence-says-its-much-more-about-your-choices-than-your-genes-251054">original article</a>.</em></p> <p><em>Image: Shutterstock</em></p> </div>

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To tip or not to tip? Kyle weighs in on the great debate

<p>In a country where tipping is about as popular as warm beer, Kyle Sandilands has somehow managed to ignite a national debate with his bold approach after revealing his personal tipping policy: doubling the bill.</p> <p>While everyday Australians are grumbling about feeling "under surveillance" by watchful waitstaff, Sandilands has effectively turned the concept of tipping on its head by making it rain on every meal.</p> <p>“Whatever the bill is, I’ll pay that again,” he declared on air, leaving co-host Jackie O and newsreader Brooklyn Ross stunned.</p> <p>The revelation has sparked a flurry of reactions, ranging from admiration to outright panic. Many hospitality workers have suddenly discovered a newfound appreciation for Sandilands, with one Sydney waiter reportedly seen frantically Googling his favourite restaurants in hopes of securing a booking.</p> <p>Meanwhile, local economists are nervously clutching their calculators. "If this catches on, we could see a rapid rise in inflation, an economic boom in hospitality, or Kyle Sandilands accidentally becoming Australia's next Reserve Bank governor," speculated one financial analyst.</p> <p>Not everyone, however, is on board with the tipping craze. Outraged anti-tipping Australians have taken to social media, decrying the practice as "un-Australian" and a gateway to the country becoming “the 51st state of America”.</p> <p>One particularly passionate commenter warned, "This is how it starts! First, it's tipping, then it's calling football ‘soccer’, and next thing you know, we’re driving on the right side of the road!"</p> <p>Despite the uproar, Sandilands seems unfazed. With his unique approach, he may have found a loophole in Australia’s new EFTPOS tipping culture – if everyone else sticks to the modest 5-25% suggested range, he might actually be saving money.</p> <p>“You’re doubling the cost,” Ross pointed out in disbelief. “I’ll save big time,” Sandilands responded, seemingly unconcerned with mathematical realities.</p> <p>As for whether his fellow Australians will follow suit or hold the line against tipping tyranny, only time will tell. One thing’s for sure: if you see Kyle Sandilands dining out, you might want to consider switching tables – and bringing an extra billfold.</p> <p><em>Images: KIIS FM</em></p>

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Shock after baseball champion's 14-year-old son dies while on family holiday

<p>The baseball world is grieving alongside former New York Yankees outfielder Brett Gardner and his family after the tragic and unexpected passing of his 14-year-old son, Miller.</p> <p>Miller Gardner died in his sleep on Friday, March 21, while on holiday with his family. According to a statement released by Brett and his wife, Jessica, through the Yankees organisation, Miller had fallen ill during the trip along with several relatives. The family did not disclose further details about the nature of the illness or their location at the time.</p> <p>“We have so many questions and so few answers at this point,” the grieving parents shared. “Miller was a beloved son and brother, and we cannot yet comprehend our life without his infectious smile.”</p> <p>Brett and Jessica, who also share an older son, Hunter, requested privacy as they mourn and seek healing. They described Miller as a vibrant and adventurous young boy who had a passion for football, baseball, golf, hunting and fishing.</p> <p>“He lived life to the fullest every single day,” they wrote, adding their gratitude to those who have offered condolences and support. They also extended their thoughts to other families who have suffered similar losses, saying, “We share their grief.”</p> <p>The Yankees, where Brett Gardner spent his entire 14-season Major League Baseball career, also released a heartfelt statement. They described Miller as having “a spark in his eyes, an outgoing and feisty personality, and a warm and loving nature.”</p> <p>“Words feel insignificant and insufficient in trying to describe such an unimaginable loss,” the team shared on social media. “It wasn’t just Brett who literally grew up in this organisation for more than 17 years – so did his wife, Jessica, and their two boys, Hunter and Miller.”</p> <blockquote class="twitter-tweet"> <p dir="ltr" lang="en">Statement from Brett and Jessica Gardner: </p> <p>With heavy hearts we are saddened to announce the passing of our youngest son, Miller. He was 14 years old and has left us far too soon after falling ill along with several other family members while on vacation. We have so many… <a href="https://t.co/lBCBVmKGUe">pic.twitter.com/lBCBVmKGUe</a></p> <p>— New York Yankees (@Yankees) <a href="https://twitter.com/Yankees/status/1903854341737386272?ref_src=twsrc%5Etfw">March 23, 2025</a></p></blockquote> <p>Brett Gardner, now 41, was a key part of the Yankees’ 2009 World Series-winning team and became a fan favourite for his grit and dedication to the game. </p> <p>Messages of love and prayers continue to pour in, a testament to the impact Miller had on those who knew him and to the deep respect held for Brett and his family.</p> <p><em>Images: X (formerly Twitter)</em></p>

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